Evaluation Of The Effectiveness Of Colon Cancer Screening Program Conducted in Our Region

Abstract

ÖZAmaç: Kolon kanseri tarama programı (KKTP) kapsamında birinci basamaktan kliniğimize yönlendirilen herhangi bir yakınması olmayıp GGK pozitifliği saptanan ardışık 300 olguya yapılan kolonoskopi sonuçları ile Sağlık Bakanlığınca bölgemizde yürütülen KKTP'nin etkinliğini araştırmayı amaçladık. Yöntem: Çalışmaya alınan bireylerin demografik özellikleri, kolonoskopi bulguları, patolojik tanıları ve tedavi sonuçları retrospektif olarak incelendi. Bulgular: Olguların 180'i kadın (%60), idi. On iki hastada (%4) kolorektal kanser (KRK) belirlendi. Bir hastada geniş tabanlı, sesil polipte yüksek grade displazili, tübülovillöz adenom saptandı. Bu 13 hastaya erken evrede laparoskopik olarak onkolojik prensiplere uygun cerrahi uygulandı. Toplamda 120 olguya prekanseröz adenomatöz polipler nedeni ile polipektomi uygulandı; bunların 30'unda (%10) yüksek gradeli displazi (YGD) saptandı. Kırkiki olguda (%14) benign anorektal hastalıklar (BAH) (fissür, hemoroid vb.) saptandı. Yirmi yedi (% 9) olguda divertiküler hastalık belirlendi. Patoloji sonucu ile 9 olguya (%3) ülseratif kolit ve 19 olguya (%6.3) nonspesifik kolit tanısı konuldu. Seksensekiz olguda (%29.3) normal kolonoskopik bulgular rapor edildi. Sonuç: Asemptomatik safhada kolon kanseri saptanan oniki ve bir geniş tabanlı YGD'li sesil polipli, olguya erken evrede cerrahi uygulanmıştır. Yüz yirmi olguda prekanseröz adenomatöz poliplere, polipektomi uygulanmış ve kolonoskopik takibe alınmıştır. Türkiyede KKTP'nin yaygınlaştırılması, etkin uygulanması ile erken teşhis ve tedavi oranlarının artacağı aynı zamanda KRK mortalite ve morbiditesinde önemli azalma olabileceği düşüncesindeyiz.Anahtar kelimeler: kolorektal kanser tarama programı, gaitada gizli kan, tarama kolonoskopisi, kolon polibi ABSTRACT Introduction: In order to search the success and efficacy of Colon Cancer Screening Program (CCSP), we aimed to evaluate the colonoscopic results of FOBT-positive 300 consecutive individuals that have been refered to our clinic within the scope of screening program. Method: Demographic features, colonoscopic findings, pathologic results, final diagnosis and treatment results of individuals were examined retrospectively. Results: A hundred and eighty (60%) individuals were women and 120 (40%) individuals were men. The median age of the individuals was 56 (50-70) years. Colorectal carcinoma (CRC) was detected in 12 (4%) patients. İn one patient tubulovillous adenoma with high grade dysplasia (HGD) was detected in broad-based sessile polyp. Laparoscopic surgery in compliance with oncologic principles was performed in these thirteen patients during the early stage of the disease. Precancerous adenomatous polyps were detected in 120 (40%), and high grade dysplasia (HGD) in 30 (10%) patients. In 42 individuals, benign anorectal diseases (fissure, hemorrhoids) were detected. Twenty-seven (9%) individuals had diverticulosis. According to pathologic results, nine (3%) patients were diagnosed as ulcerative colitis and nineteen (6.3%) patients as nonspecific colitis. Eighty-eight individua...

How Effective is a Fecal Occult Blood Test to Detect Malignancy?

“…In both studies, the rates of FOBT positivity and FOBT positivity according to gender were similar, and gender had no effect on the test result. Contrary to our study, in the study of Kara et al 16 , 60% of the 300 patients with positive FOBT were female and 40% were male, and they found the rate of test positivity higher in females.…”

“…reported a 7.1% CRC detection rate in their series of 53,332 cases of FOBT positivity in the screening group, and our findings were similar to several similar studies 12,18 . There are also studies with a lower rate of CRC compared to our study 15,16,19 .…”

Distribution of Colon Lesions in Elderly

“…Yanık et al found the rate of colorectal carcinoma to be 12.31% in elderly patients (10). In a recent study conducted by Kara et al, the incidence of colon carcinoma was 4% and the most frequent localization of the colon carcinoma was descending colon (25%) (17). In our study, the most common localization of the colon carcinoma was rectum.…”