Evaluation of the effectiveness of a moisturizing cream as an adjuvant in the treatment of eczema: A preliminary real-world study report

Abstract

Objectives: Eczema is a papulosquamous disease characterized by itchy, dry, rough, flaky, inflamed, and irritated skin on arms, inner elbows, backs of the knees, or head. Numerous skin conditions can be managed with the help of moisturizers. Venusia® Max is a moisturizing cream meant for eczema with a unique combination of four butters – shea, cocoa, mango, and aloe that act as emollients along with glycerin, propylene glycol, emulsifying wax, and cyclomethicone. The study’s objective is to assess Venusia® Max cream’s moisturizing efficacy when used as an adjuvant to the main line of treatment for eczema. Material and Methods: This monocentric, real-world setting study evaluates the effectiveness of Venusia® Max as an adjuvant, along with prescribed treatment in patients with eczema, versus prescribed treatment only (without Venusia® Max) as well as baseline. One hundred and twenty subjects enrolled in the study were divided in two groups: 1. Receiving Venusia® Max cream as an adjuvant, along with prescribed treatment and 2. receiving prescribed treatment only. The subjects were assessed for eczema area and severity index (EASI) scores, skin hydration using moisture meter-SC, transepidermal water loss (TEWL) using VapoMeter, and subject self-assessment of itching, cutaneous dryness, and burning sensation. Results: In the group with Venusia® Max cream, significant reduction in the EASI score, burning sensation, itching, and TEWL along with significant increase in skin hydration was observed when compared to baseline. Conclusion: Thus, Venusia® Max cream offers a novel and effective topical treatment for the dry skin of eczema patients.