Evaluation of the effects of osteopathic manipulative treatment associated with transcranial direct current stimulation in chronic nonspecific low back pain. A protocol for a randomised controlled trial

Armbrust, Danilo; Fonseca, Carlos Luques; Lopes, Jamile Benite Palma; Trindade, Andrei Machado Viegas da; Neto, Hugo Pasin; Oliveira, Cláudia Santos

doi:10.1016/j.ijosm.2023.100679

International Journal of Osteopathic Medicine

2023

DOI: 10.1016/j.ijosm.2023.100679

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Evaluation of the effects of osteopathic manipulative treatment associated with transcranial direct current stimulation in chronic nonspecific low back pain. A protocol for a randomised controlled trial

Danilo Armbrust

Carlos Luques Fonseca

Jamile Benite Palma Lopes

et al.

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2024

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Combining Transcranial Direct Current Stimulation With Non-Invasive Interventions for Chronic Primary Pain: A Systematic Review and Meta-Analysis

Lyra de Brito Aranha,

Nascimento,

Sampaio

et al. 2024

Neurorehabil Neural Repair

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Background A growing number of studies has combined transcranial direct current stimulation (tDCS) with other non-invasive non-pharmacological therapies (NINPT) to enhance effects in pain reduction. However, the efficacy of these combined approaches in treating chronic primary pain (CPP) warrants thorough investigation. Objective This study aims to evaluate the efficacy of tDCS in conjunction with other NINPT in alleviating pain severity among CPP patients. Methods We conducted a systematic search for randomized controlled trials (RCTs) comparing the efficacy of tDCS combined with NINPT against control treatments in adult CPP patients. The search spanned multiple databases, including PubMed, EMBASE, LILACS, Scopus, Web of Science, and CENTRAL. Results Our systematic review included 11 RCTs with a total of 449 participants. In our meta-analysis, which comprised 228 participants receiving active-tDCS and 221 receiving sham-tDCS, we found a significant reduction in pain intensity (Standard Mean Difference = −0.73; 95% Confidence Interval (CI) = −1.18 to −0.27; P = .002) with the use of active-tDCS combined with NINPT. Conclusion These findings substantiate the therapeutic potential of combining tDCS with other NINPT, highlighting it as an effective treatment modality for reducing pain intensity in CPP patients.

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Combining Transcranial Direct Current Stimulation With Non-Invasive Interventions for Chronic Primary Pain: A Systematic Review and Meta-Analysis

Lyra de Brito Aranha,

Nascimento,

Sampaio

et al. 2024

Neurorehabil Neural Repair

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show abstract

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Evaluation of the effects of osteopathic manipulative treatment associated with transcranial direct current stimulation in chronic nonspecific low back pain. A protocol for a randomised controlled trial

Cited by 1 publication

References 58 publications

Combining Transcranial Direct Current Stimulation With Non-Invasive Interventions for Chronic Primary Pain: A Systematic Review and Meta-Analysis

Combining Transcranial Direct Current Stimulation With Non-Invasive Interventions for Chronic Primary Pain: A Systematic Review and Meta-Analysis

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