2020
DOI: 10.1016/j.pdpdt.2019.101596
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Evaluation of the efficacy of 5-aminolevulinic acid photodynamic therapy for the treatment of vulvar lichen sclerosus

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Cited by 17 publications
(11 citation statements)
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“…5-Aminolevulinic acid (ALA), methyl aminolevulinate (MAL; Metvix), and Hexvix/Cysview are precursors of protoporphyrin IX, which absorbs at 630 nm [ 28 , 29 ]. They were granted FDA approvals and are used to treat glioblastoma, basal cell carcinoma, Bowen disease, prostate, bladder, and colon cancers [ 30 , 31 , 32 ]. Meta-tetrahydroxy phenyl chlorin (m-THPC, temoporfin), excitation wavelength of ~652 nm, is approved in the EU to treat biliary and pancreatic cancers and breast cancer metastases.…”
Section: Photodynamic Therapy In Treating Cancermentioning
confidence: 99%
“…5-Aminolevulinic acid (ALA), methyl aminolevulinate (MAL; Metvix), and Hexvix/Cysview are precursors of protoporphyrin IX, which absorbs at 630 nm [ 28 , 29 ]. They were granted FDA approvals and are used to treat glioblastoma, basal cell carcinoma, Bowen disease, prostate, bladder, and colon cancers [ 30 , 31 , 32 ]. Meta-tetrahydroxy phenyl chlorin (m-THPC, temoporfin), excitation wavelength of ~652 nm, is approved in the EU to treat biliary and pancreatic cancers and breast cancer metastases.…”
Section: Photodynamic Therapy In Treating Cancermentioning
confidence: 99%
“…Photodynamic therapy (PDT) with the use of topical 10% 5-ALA cream (5-aminolaevulinic acid) has been found to be useful in treating VLS [32]. In a study, after application of freshly prepared 10% 5-ALA cream with a one-cm margin and incubating for three hours, the lesions were irradiated with 100 J/cm 2 633 nm red light at 100 mW/cm 2 [33].…”
Section: Photodynamic Therapymentioning
confidence: 99%
“…Further data are provided by some noncomparative studies including prospective cohorts and case series [199][200][201][202][203][204][205][206][207]. The majority of the patients included in these studies were treated with 5-ALA before the application of radiation (5-ALA PDT), whereas the remaining patients with methyl-aminolevulinate (methyl-PDT).…”
Section: Photodynamic Therapymentioning
confidence: 99%