Evaluation of The Efficacy of Bupivacaine Soaked in Gelfoam® at the Iliac Crest Bone Graft Site

Gamlı, Mehmet; Dalgıç, Ali; Ornek, Dilsen; Horasanlı, Eyüp; Kilci, Oya; Ün, Canan; Dikmen, Bayazıt

doi:10.1016/s0034-7094(12)70181-2

Cited by 9 publications

(8 citation statements)

References 10 publications

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“…On contrary, local application of bupivacaine soaked gelfoam at the site of iliac graft operations failed to reveal any significant difference in VAS pain scores in comparison to the use of parenteral opioid although the required narcotic dosage was significantly less in bupivacaine group at 24 and 48 hours (14).…”

Section: Discussionmentioning

confidence: 72%

Analgesic efficacy and safety of absorbable gelatin sponge soaked with bupivacaine or bupivacaine and lidocaine in Cesarean section wounds

Mohamed

El-Din

El-Zaher

et al. 2022

Minia Journal of Medical Research

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Background: Management of acute postoperative pain is one of the major challenges after CS. Administration of local anesthetic through wound instillation is an alternative to avoid opioids drawbacks. The aim of the study is to evaluate and compare the efficacy and safety of placement of subcutaneous gelatin sponge soaked with either bupivacaine 0.25% or a mixture of bupivacaine 0.25% and lidocaine 2% for postoperative analgesia after elective CS under general anesthesia. Methods: A total 105 parturient were equally allocated into either: Group C (control): received gelfoam soaked with 20 ml of 0.9% normal saline, Group B: received gel-foam soaked with 20 ml bupivacaine 0.25% or Group BL: received gel-foam soaked with a mixture of 10ml bupivacaine 0.25% and 10 ml lidocaine2%. Perioperative heamodynamics, visual analogue scale for pain (VASP), 1st analgesic request, total analgesic requirements, side effects and wound healing were recorded. Results: significantly lower heamodynamics, VASP at 1, 2, 8, 12& 24 hrs. and postoperative nausea and vomiting with lower total analgesics consumption were recorded in B&BL groups compared to C group. Analgesia was of earlier onset in BL group but more intense at 4hrs. in B group, otherwise the two groups were comparable. No wound healing complications were recorded in all groups. Conclusion: Gelatin-sponge soaked with bupivacaine or a mixture of lidocaine and bupivacaine in CS wounds was safe and effective in providing better heamodynamics and postoperative analgesia which was earlier in onset in mixture group but more profound in bupivacaine group with narrow clinical difference between the two groups.

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Section: Discussionmentioning

confidence: 72%

Analgesic efficacy and safety of absorbable gelatin sponge soaked with bupivacaine or bupivacaine and lidocaine in Cesarean section wounds

Mohamed

El-Din

El-Zaher

et al. 2022

Minia Journal of Medical Research

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“…To minimize postoperative donor site pain, preemptive analgesia strategies have been employed including intravenous analgesics, intraoperative local anesthetic sponges, nerve blocks, and local anesthetic infusion pumps (Wilkes and Thomas, 1994; Hahn et al, 1996; Hoard et al, 1998; Blumenthal et al, 2005; Singh et al, 2005; Singh et al, 2007; Coulthard et al, 2008; Dashow et al, 2009; Ouaki et al, 2009; Isyanov and Suresh, 2009; Sbitany et al, 2010; Meara et al, 2011; Gamli et al, 2012; Visoiu, 2014; Muzaffar et al, 2016). Intraoperative use of bupivacaine at the iliac crest donor site has been shown to delay the onset of pain, decrease postoperative opioid use, and lead to earlier ambulation (Hoard et al, 1998; Dashow et al, 2009; Gamli et al, 2012). Recent studies of indwelling pain catheters have reported conflicting findings regarding length of hospitalization after iliac crest bone graft (ICBG) for secondary alveolar reconstruction (Sbitany et al, 2010; Meara et al, 2011; Muzaffar et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

A Multimodal Preemptive Analgesic Protocol for Alveolar Bone Graft Surgery: Decreased Pain, Hospital Stay, and Health Care Costs

Bykowski

Sivak

Garland

et al. 2018

The Cleft Palate Craniofacial Journal

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“…The advent of techniques such as minimally invasive trephine drill harvest and placement of continuous-infusion pain pumps has made outpatient ABG an increasingly feasible and cost-effective procedure 4,11–13 . Multiple methods have been described to control donor site pain in patients receiving ABG including opioids, non-steroidal anti-inflammatory drugs, local anesthetic injections or nerve blocks, 14–16 anesthetic sponges, 15,17 and placement of continuous-infusion pain pumps 8,12,13,18–23 …”

mentioning

confidence: 99%

It’s Hip to Go Home: An Evaluation of Outpatient Alveolar Bone Grafting in Patients With Cleft Palate

Mitchell,

Obinero,

Ekeoduru

et al. 2023

Journal of Craniofacial Surgery

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Introduction: Secondary alveolar bone grafting (ABG) is a common procedure performed at cleft care centers used to fill the alveolar cleft. The advent of techniques such as minimally invasive trephine drill harvest and placement of continuous-infusion pain pumps at the donor site has made outpatient ABG an increasingly feasible and cost-effective procedure. However, enhanced recovery after surgery protocols to maximize pain control and recovery times for this patient population have not been well established. Methods: A retrospective single-institution review was conducted of pediatric patients with cleft palate who underwent iliac crest bone graft ABG at a large urban academic children’s hospital from 2017 to 2022. Patient age, alveolar cleft repair laterality, pain scores, surgery duration, hospital LOS, readmissions, and re-operations within 30 days were examined. Results: Fifty-four patients met our inclusion criteria. Fifty patients (92.6%) received a pain pump during the operation. The median duration of surgery and LOS in the post-anesthesia care unit were 1.28 and 1.75 hours, respectively. Fifty-two patients (96.3%) were discharged on the same day as their surgery whereas 2 patients (3.7%) stayed in the hospital overnight. The median pain score at the time of discharge was 0 (interquartile range 0, 0). There were 6 (11.1%) minor complications including 5 pain pump malfunctions and 1 recipient site wound breakdown. There was 1 readmission (1.9%) for development of a surgical site infection at the hip and no re-operations within 30 days of surgery. Conclusion: The described outpatient ABG protocol demonstrates effective postoperative pain control, short hospital LOS, and few complications requiring hospital readmission or reoperation.

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Evaluation of The Efficacy of Bupivacaine Soaked in Gelfoam® at the Iliac Crest Bone Graft Site

Abstract: This study has demonstrated that bupivacaine soaked in gelfoam at the iliac bone graft harvest site reduced postoperative parenteral opioid usage.

Cited by 9 publications

References 10 publications

Analgesic efficacy and safety of absorbable gelatin sponge soaked with bupivacaine or bupivacaine and lidocaine in Cesarean section wounds

Analgesic efficacy and safety of absorbable gelatin sponge soaked with bupivacaine or bupivacaine and lidocaine in Cesarean section wounds

A Multimodal Preemptive Analgesic Protocol for Alveolar Bone Graft Surgery: Decreased Pain, Hospital Stay, and Health Care Costs

It’s Hip to Go Home: An Evaluation of Outpatient Alveolar Bone Grafting in Patients With Cleft Palate

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