Evaluation of the Efficacy of Coronary Risk Index, a New Scoring System for Predicting Morbidity and Severity of Coronary Stenosis in Patients Undergoing Coronary Angiography.

Seki, Makoto; Ishiguro, Toshihiko; Gyohda, Yasuaki; Ohsato, Shohjiroh; Yokota, Miyuki

doi:10.2199/jjsca.18.271

“…To predict atherosclerosis and cardiovascular problems, the atherogenic indices (atherogenic index of plasma (AIP); atherogenic coefficient (AC); coronary risk index (CRI)) were calculated using the following equations [ 39 , 40 , 41 ]: AIP = Log 10 [TG/HDL-c] AC = [TC − HDL-c/HDL-c] CRI = [TC/HDL-c] …”

Section: Methodsmentioning

confidence: 99%

“…To predict atherosclerosis and cardiovascular problems, the atherogenic indices (atherogenic index of plasma (AIP); atherogenic coefficient (AC); coronary risk index (CRI)) were calculated using the following equations [39][40][41]: Following anesthesia, excised inguinal fat was fixed by immersion in 4% formaldehyde in 0.1 M phosphate buffer overnight at 4 • C, washed inPBS, dehydrated in a graded series of ethanol, cleared in xylene, and embedded in paraffin. The paraffin blocks from each group were cut with a microtome into 5 µm thick sections, stained with hematoxylin and eosin (H&E), and inspected under a light microscope (×400, Olympus, Germany) equipped with a digital camera system (Carl Zeiss camera, model Axiocam ERc 5s.…”

Section: Measurement Of Lipid Profiles and Atherogenic Indicesmentioning

confidence: 99%

Time-Restricted Feeding Improves Body Weight Gain, Lipid Profiles, and Atherogenic Indices in Cafeteria-Diet-Fed Rats: Role of Browning of Inguinal White Adipose Tissue

Aouichat

¹

,

Chayah

²

,

Bouguerra-Aouichat

³

et al. 2020

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Time-restricted feeding (TRF) showed a potent effect in preventing obesity and improving metabolicoutcomes in several animal models of obesity. However, there is, as of yet, scarce evidence concerning its effectiveness against obesogenic challenges that more accurately mimic human Western diets, such as the cafeteria diet. Moreover, the mechanism for its efficacy is poorly understood. White adipose browning has been linked to body weight loss. Herein, we tested whether TRF has the potential to induce browning of inguinal white adipose tissue (iWAT) and to attenuate obesity and associated dyslipidemia in a cafeteria-diet-induced obesity model. Male Wistar rats were fed normal laboratory chow (NC) or cafeteria diet (CAF) for 16 weeks and were subdivided into two groups that were subjected to either ad libitum (ad lib, A) or TRF (R) for 8 h per day. Rats under the TRF regimen had a lower body weight gain and adiposity than the diet-matchedad lib rats, despite equivalent levels of food intake and locomotor activity. In addition, TRF improved the deranged lipid profile (total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL-c), low-density lipoprotein (LDL-c)) and atherogenic indices (atherogenic index of plasma (AIP), atherogenic coefficient (AC), coronary risk index (CRI) in CAF-fed rats. Remarkably, TRF resulted in decreased size of adipocytes and induced emergence of multilocular brown-like adipocytes in iWAT of NC- and CAF-fed rats. Protein expression of browning markers, such as uncoupling protein-1 (UCP1) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α), were also up-regulated in the iWAToftime-restricted NC- or CAF-fed rats. These findings suggest that a TRF regimen is an effective strategy to improve CAF diet-induced obesity, probably via a mechanismthe involving WAT browning process.

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“…To predict atherosclerosis and cardiovascular problems, atherogenic index (AI), atherogenic index of plasma (AIP) and coronary risk index (CRI) were determined referring to the equations given below: 42,44,45 AI…”

Section: Vldl-c ¼ Tg/5mentioning

confidence: 99%

Preventive effect of goby fish protein hydrolysates on hyperlipidemia and cardiovascular disease in Wistar rats fed a high-fat/fructose diet

Nasri

¹

,

Abdelhedi

²

,

Jemil

³

et al. 2018

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“…To predict atherosclerosis and cardiovascular problems, atherogenic index (AI), atherogenic index of plasma (AIP) and coronary risk index (CRI) were determined referring to the equations given below: AI = LDL-c / HDL-c [22] AIP = log (TG/HDL-c) [24] CRI = TC / HDL-c [25].…”

Section: Determination Of Serum and Liver Biomarkers 271 Serum Lipmentioning

confidence: 99%

Hypolipidemic, antiobesity and cardioprotective effects of sardinelle meat flour and its hydrolysates in high-fat and fructose diet fed Wistar rats

Jemil

¹

,

Abdelhedi

²

,

Nasri

³

et al. 2017

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Evaluation of the Efficacy of Coronary Risk Index, a New Scoring System for Predicting Morbidity and Severity of Coronary Stenosis in Patients Undergoing Coronary Angiography.

Cited by 7 publications

References 4 publications

Time-Restricted Feeding Improves Body Weight Gain, Lipid Profiles, and Atherogenic Indices in Cafeteria-Diet-Fed Rats: Role of Browning of Inguinal White Adipose Tissue

Time-Restricted Feeding Improves Body Weight Gain, Lipid Profiles, and Atherogenic Indices in Cafeteria-Diet-Fed Rats: Role of Browning of Inguinal White Adipose Tissue

Preventive effect of goby fish protein hydrolysates on hyperlipidemia and cardiovascular disease in Wistar rats fed a high-fat/fructose diet

Hypolipidemic, antiobesity and cardioprotective effects of sardinelle meat flour and its hydrolysates in high-fat and fructose diet fed Wistar rats

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