Evaluation of the Efficacy of Polidocanol in the Form of Foam Compared With Liquid Form in Sclerotherapy of the Greater Saphenous Vein

Hamel-Desnos, C.; Desnos, P.; Wollmann, Jan-Christoph; Ouvry, P.; Mako, Serge; ALLAERT, FRANÇOIS-ANDRE

doi:10.1097/00042728-200312000-00003

Cited by 38 publications

(41 citation statements)

References 2 publications

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“…Two ml of POL (Aetoxysclerol® tamponné/lauromacrogol 400 (Kreussler Pharma, Germany) were used at 0.3% and 8 ml of air. Pumping and passing from one syringe to the other 15 times, produces stable micro-foam following the Tessari technique (Cavezzi et al, 2002;Frullini, 2000;Hamel-Desnos et al, 2003;Tessari, 2001;Tessari et al 2001;Wollmann, 2004). The resulting foam is rich in nitrogen, with an irregular bubble size and a highly internal cohesion (Redondo and Cabrera , 2005).…”

Section: Methodsmentioning

confidence: 99%

Applications of Polidocanol in Varicose Vein Treatment Assisted by Exposure to Nd:YAG Laser Radiation

Smarandache¹,

Moraga²,

Staicu³

et al. 2012

Nd YAG Laser

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Section: Methodsmentioning

confidence: 99%

Applications of Polidocanol in Varicose Vein Treatment Assisted by Exposure to Nd:YAG Laser Radiation

Smarandache¹,

Moraga²,

Staicu³

et al. 2012

Nd YAG Laser

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“…A single injection (the protocol did not include further injections) of 2 to 2.5 mL of double‐syringe‐system foam or 3% liquid polidocanol showed a 2‐year occlusion rate of 84% in the foam group versus 40% in the fluid group. Vasospasm was clearly more frequent and more pronounced in the group treated with foam (mean length 28 cm) than in the control group, the rate of side effects being identical 11,12 …”

Section: Resultsmentioning

confidence: 96%

“…The efficacy of the foam generated by agitation of the syringe or drug vial was increased approximately 3.5‐ to 4‐fold compared with the same amount of “conventional” fluid. The observation of a “marked vasospasm” after injection of foam is nowadays considered to be an important immediate end point for the assessment of the efficacy of modern sclerotherapy 11–13 . This (reversible) vasospasm, which is often clearly detectable in duplex‐guided sclerotherapy, can be considered to be a sign of initial vascular damage after sclerotherapy.…”

Section: Resultsmentioning

confidence: 99%

The History of Sclerosing Foams

Wollmann¹

2004

Dermatol Surg

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“…This normally occurs within 10-30 s after foam injection, although in some cases it is only seen after several minutes. There is no consensus as to whether the magnitude of the venospasm correlates with the quality of the sclerosing foam (Hamel-Desnos 2003). Usually, the venospasm is so intense that it compresses the foam column, causing an even spread along the incompetent vein segment (Fig.…”

Section: Ultrasound Evaluation Of the Sclerosant Reactionmentioning

confidence: 99%

Duplex Sonography and Venography for Interventions

Mendoza¹,

Gerlach²

2014

PanVascular Medicine

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Disorders of the superficial leg veins are very common. Ultrasound has become the principal diagnostic modality for the anatomy, physiology, and various disorders of the superficial veins. This caused a gradual change in the criterion standard of investigation of leg veins from venography to duplex sonography.This chapter discusses the basics of flow and reflux in leg veins as represented by ultrasound. Different provocation maneuvers are described to elicit a blood flow that may result in a reflux. The ultrasound anatomy of the saphenous veins, their junctions, and the perforating veins is described, followed by a description of the typical flow patterns in healthy and incompetent valve situations.Ultrasound is required to establish a diagnosis of leg vein insufficiency and to measure its extension into the lower extremities' venous system, thus facilitating a treatment decision. It is also indispensable for most of the current treatment modalities before, during, and after the intervention. Ultrasound is of critical importance when deciding which treatment would be best and for identifying suitable (or unsuitable) treatment alternatives. It is excellent for postoperative evaluation, identification of complications, and both short-and long-term follow-up. The importance of duplex sonography for treatment is highlighted in this chapter. Also described are the use of ultrasound for preoperative decisions, mapping for stripping and conservative hemodynamic correction of venous insufficiency (CHIVA) or selective varicose vein ablation under local anesthesia, and intraoperative monitoring in foam sclerotherapy, external valvuloplasty, and endoluminal treatments of saphenous veins.Although venography has been replaced by ultrasound to a large extent over recent decades, venography remains a comprehensive, fast method for the investigation of the venous system, with unsurpassed documentation. Venography not only allows detailed anatomic representation, but also qualitative and functional analyses. It is still the only method for the objective documentation of anatomic conditions and spatial interrelations, which may be of importance for the strategic planning of surgery and for the interpretation of the overall condition. However, today venography is only used in special, individual cases before performing surgery and interventions in the superficial venous system. Although magnetic resonance venography, computed tomography, and computed angiography are evolving, they do not yet represent standard diagnostic modalities for the superficial venous system; they are currently used for the diagnostic workup of iliac veins, for example. Glossary of TermsAASV Accessory anterior saphenous vein APSV Accessory posterior saphenous vein

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Evaluation of the Efficacy of Polidocanol in the Form of Foam Compared With Liquid Form in Sclerotherapy of the Greater Saphenous Vein

Cited by 38 publications

References 2 publications

Applications of Polidocanol in Varicose Vein Treatment Assisted by Exposure to Nd:YAG Laser Radiation

Applications of Polidocanol in Varicose Vein Treatment Assisted by Exposure to Nd:YAG Laser Radiation

The History of Sclerosing Foams

Duplex Sonography and Venography for Interventions

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