Evaluation of the Fermented Products of <i>Fructus Ligustri Lucidi</i> for Use as Raw Materials in Functional Health Foods and Cosmetics

Li, Jing-Jing; Kim, Kyoung-Hee; Yook, Hong-Sun

doi:10.3746/jkfn.2023.52.7.691

Cited by 4 publications

(1 citation statement)

References 44 publications

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“…Fermented cosmetics are emerging as a trend in the domestic cosmetics market and several domestic major companies introducing cosmetics that utilize fermentation techniques, resulting in high sales and rapid growth (Lee et al, 2010). Various studies have been conducted to increase the biological activity and active ingredients of natural products through probiotic fermentation (Li et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

Whitening effects of fermented Trigonotis radicans var. sericea with Lactobacillus brevis in α-MSH-stimulated B16F10 melanoma cells

Jeong,

Kim,

Cho

2024

Food Sci. Preserv.

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This study was designed to compare the whitening effects of 60% ethanol extracts of Trigonotis radicans var. sericea (TR) and Lactobacillus brevis-fermented T. radicans var. sericea (FTR). Measurement of cytotoxicity in B16-F10 melanoma cells to confirm the whitening effect, FTR showed higher cell viability than TR. FTR showed inhibitory activity on melanin contents similar to the normal group at concentrations of 50 and 100 μg/mL. MITF expression was used to confirm the effect on melanogenesis-related protein expression. TR and FTR showed significant concentration-dependent decrease, and FTR showed lower expressions than the normal group at concentrations of 25, 50, and 100 μg/mL. Additionally, the mRNA expression of melanogenesis-related genes (MC1R, Rab27a, TGF-β1 and Myo5a) were measured by RT-qPCR to confirm the whitening effect. In MC1R expression at a concentration of 100 μg/mL in FTR showed effective inhibitory activities, and in TGF-β1 expression, TR and FTR both showed effective activities compared to normal groups even at low concentrations. Results of myo5a and Rab27a, a similar pattern was shown, and FTR showed effective inhibitory activities at a concentration of 100 μg/mL. As a result, FTR had higher whitening effects through bioconversion and is expected to be a good material for whitening functional cosmetics.

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Section: Introductionmentioning

confidence: 99%

Whitening effects of fermented Trigonotis radicans var. sericea with Lactobacillus brevis in α-MSH-stimulated B16F10 melanoma cells

Jeong,

Kim,

Cho

2024

Food Sci. Preserv.

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Effects on antioxidant, whitening, and anti-wrinkle improvement of ethanol extracts from fermented Trigonotis radicans var. sericea by Lactobacillus brevis

Jeong,

Kim,

Kim

et al. 2024

Food Sci. Preserv.

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This study was designed to compare the effects on antioxidant, whitening, and anti-wrinkle improvement of 60% ethanol extracts from Trigonotis radicans var. sericea (TR) and Lactobacillus brevis-fermented T. radicans var. sericea (FTR). The total phenolics contents of TR was 18.6 mg/g, and FTR was 18.2 mg/g. The HPLC analysis confirmed more phenolic compounds were produced in FTR by bioconversion than in TR. The FTR showed higher 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity than TR. The results of the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation decolorization assay, FTR and TR showed higher activity than BHT (positive control). The FTR (1.21-1.29 PF) showed higher antioxidant protection factor (PF) activity than the TR (1.15-1.22 PF) and showed higher tyrosinase, collagenase and elastase inhibitory activities. This results showed L. brevis-fermentation of Trigonotis radicans var. sericea changed the composition profile and has effects on antioxidant, whitening and anti-wrinkle improvement.

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Physicochemical Properties and Biological Activities of Fermented Ocimum bacilicum L. Extracts with Various Microorganisms

Lee,

Yook

2024

JKFN

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Evaluation of the Fermented Products of Fructus Ligustri Lucidi for Use as Raw Materials in Functional Health Foods and Cosmetics

Cited by 4 publications

References 44 publications

Whitening effects of fermented Trigonotis radicans var. sericea with Lactobacillus brevis in α-MSH-stimulated B16F10 melanoma cells

Whitening effects of fermented Trigonotis radicans var. sericea with Lactobacillus brevis in α-MSH-stimulated B16F10 melanoma cells

Effects on antioxidant, whitening, and anti-wrinkle improvement of ethanol extracts from fermented Trigonotis radicans var. sericea by Lactobacillus brevis

Physicochemical Properties and Biological Activities of Fermented Ocimum bacilicum L. Extracts with Various Microorganisms

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