Evaluation of the hand anthropometric measurement in ADHD children and the possible clinical significance of the 2D: 4D ratio

Buru, Ece; Gözil, Rabet; Bahçelioğlu, Meltem; Özkan, Seçil; İşeri, Elvan

doi:10.5505/ejm.2017.73792

Cited by 5 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The digit ratio of the right and left hands was reported to be significantly differed in males and females with attention deficit and hyperactivity disorder compared to that in healthy individuals. 24 Children with autism spectrum disorders showed to have lower right hand digit ratio compared to the normal children. 25 The patients with schizophrenia showed to have significantly higher right hand digit ratio compared to the control group in both sexes; and the same association was found with the left hand too in females.…”

Section: Discussionmentioning

confidence: 92%

Association of Digit Ratio With Depression and Hopelessness in Females

Aliabadi

Zendehboodi

2021

Int J Basic Sci Med

View full text Add to dashboard Cite

Introduction: Depression is regarded as the main cause of individual’s incapacity. One of the component of depression is hopelessness. This study was planned to examine if the digit ratio associates with depression and hopelessness status in the Iranian women. Methods: This cross-sectional study sample included 358 women aged between 20 to 32 years old. The palm side of both hands of individuals was photographed and then the length of index and ring fingers was measured by ImageJ. The Beck’s depression inventory II and Beck’s hopelessness scale (BHS) were used to measure the levels of depression and hopelessness respectively. ANOVA and Student’s t test was applied to compare the study groups in respect to the continuous data. Results: The results showed that the means of 2D:4D ratio of neither right nor left hands were significantly different between the depression study groups. The same insignificant results were derived with hopelessness status too. However, reanalyzing the data, while combination of depression and hopelessness was considered, showed a significantly lower digit ratio of the right hand in the women whit neither depression nor hopelessness (group 1) compared to the women with moderate/severe depression while holding a degree of hopelessness (group 2) (ratio mean for group 1: 0.978 ± 0.003 and for group 2: 0.992 ± 0.005; t = -2.417, P = 0.017). Conclusion: Our data suggested that the 2D:4D ratio of the right hand in the women associates with the severity of depression when accompanied by hopelessness.

show abstract

Section: Discussionmentioning

confidence: 92%

Association of Digit Ratio With Depression and Hopelessness in Females

Aliabadi

Zendehboodi

2021

Int J Basic Sci Med

View full text Add to dashboard Cite

show abstract

“…Characteristics of the included studies about 2D:4D ratio in patients with neurodevelopmental disorders are reported in Table 1 [ 31 - 51 ].…”

Section: Resultsmentioning

confidence: 99%

“…The quality of the studies included in the systematic review and meta-analysis has been reported in Table 6 . Two studies were judged with a score of 4 out of 9 points [ 41 , 42 ], four studies with 5 out of 9 [ 49 , 55 , 65 , 66 ], ten studies with 6 out of 9, four studies with 7 out of 9 and the the remaining papers with 8 or 9 stars. As concerns the study selection, we have found a relatively low risk of bias in diagnostic criteria: in fact, we included only studies in which participants had received a psychiatric diagnosis by a clinician.…”

Section: Meta-analyses Of the Included Studiesmentioning

confidence: 99%

Second-to-Fourth Digit Ratio (2D:4D) in Psychiatric Disorders: A Systematic Review of Case-control Studies

Fusar-Poli

Rodolico

Sturiale

et al. 2021

Clin Psychopharmacol Neurosci

View full text Add to dashboard Cite

The second-to-fourth digit ratio (2D:4D) is an indirect, retrospective, non-invasive measure that correlates negatively with intrauterine exposure to testosterone. The present meta-analysis aimed to evaluate if 2D:4D differs between patients with psychiatric disorders and controls. In September 2019, we searched in Web of Knowledge, PsycINFO, Embase, and CINHAL, and retrieved 619 papers. We finally included 43 case-control studies which compared the 2D:4D ratio of patients with autism spectrum disorder (ASD) (n = 16), schizophrenia (n = 8), gender non-conformity (n = 7), addictions (n = 5), attention deficit-hyperactivity disorder (ADHD) (n = 4), mood disorders (n = 2), and intellectual disability (n = 1) to non-clinical controls. Meta-analyses showed that, overall, psychiatric patients had lower 2D:4D than healthy controls (n = 43, overall sample = 9,484, mean difference = −0.0056, 95% confidence interval from −0.0093 to −0.002, I 2 = 74%), with more pronounced differences in the right hand, males, and children. Considering psychiatric disorders individually, significant differences were found in the ASD, ADHD, and addictions groups, in which 2D:4D was significantly lower than healthy controls. Conversely, the right hand of males with schizophrenia showed higher 2D:4D than healthy controls. No other significant differences were detected. Although our results need to be cautiously interpreted and find limited applications in clinical practice, they may suggest that 2D:4D is altered in some psychopathological conditions, underlining the role of prenatal exposure to sex steroids in the etiology of psychiatric disorders.

show abstract

Association between tendencies for attention-deficit/hyperactivity disorder (ADHD) and the 2D:4D digit ratio: a cross-cultural replication in Germany and China

Wernicke

Zabel

Zhang

et al. 2020

Early Human Development

View full text Add to dashboard Cite

Evaluation of the hand anthropometric measurement in ADHD children and the possible clinical significance of the 2D: 4D ratio

Abstract: This study was performed in 16th National Anatomy Congress /poster session (Publication number:3465692) Evaluation of the han d anthropometric measurement in ADHD children and the possible clinical significance of the 2D:4D ratio (2014)

Cited by 5 publications

References 23 publications

Association of Digit Ratio With Depression and Hopelessness in Females

Association of Digit Ratio With Depression and Hopelessness in Females

Second-to-Fourth Digit Ratio (2D:4D) in Psychiatric Disorders: A Systematic Review of Case-control Studies

Association between tendencies for attention-deficit/hyperactivity disorder (ADHD) and the 2D:4D digit ratio: a cross-cultural replication in Germany and China

Contact Info

Product

Resources

About