Evaluation of the hemodynamic profile in hospitalized hypertensive old age patients, using hotman® integrated hemodynamic management system

Capisizu, A.; Movileanu, Tamara; Aurelian, S.M.; Zamfirescu, A.; Vlad, Liliana; Dascalescu, R.

doi:10.1016/j.atherosclerosis.2014.05.789

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Th is phenomenon could be avoided through knowledge/evaluation of hemodynamic status and changing their actual antihypertensive medication. Drug-drug and drug-disease interactions are common in older adults and may have a negative impact on health-related quality of life 3,4,5,23 .…”

Section: Discussionmentioning

confidence: 99%

“…Numerical increase in older people and consequently the consumption of drugs, associated with morpho-functional changes of the old body, bring the elderly in relationship with drugs in diff erent position than young adults. A individual pharmaco-geriatrics are a necessity [3][4][5] especially that are a multitude of medications such as cardiovascular, gastrointestinal, central nervous system, analgesics, and vitamin agents 6,7 . Management of hypertension in the elderly raises particular challenges and has raised questions about the relationship between blood pressure (BP) lowering and risk of falls 8 knows that in the fi fth and sixth decade of life, systolic blood pressure(SBP) and diastolic blood pressure (DBP) increase linearly, after SBP continues to rise while DBP gradually decreases 9 .…”

Section: Prevalence Of Antihypertensive Medication In Studied Group Imentioning

confidence: 99%

See 1 more Smart Citation

Management of Hypertension in the Elderly by Modern Methods

Aurelian¹,

Dascalescu²,

Zamfirescu³

et al. 2018

Rev. Med. Mod.

View full text Add to dashboard Cite

Introduction: Monitoring of antihypertensive therapy is a challenge for any patient, but especially for the elderly. Management of high blood pressure in the elderly raised many questions about lowering blood pressure and the risk of falls. Methods: A cross-sectional, observational study of 150 patients; mean-age 74.68±7.49 years with antihypertensive therapy. Daily blood pressure and hemodynamic modulators (volemia, inotropism, chronotropism) were measured using thoracic electrical impedance (TEB-System HOTMAN ®). The evaluated haemodynamic profi le was correlated with each administered antihypertensive drug/class. Results: 79.5% of patients were therapeutically controlled; 93.1% had at least one modifi ed hemodynamic modulator (p <0.0001). Distribution of antihypertensive drugs: Indapamidum (85.7%), Carvedilolum (42.9%), Perindoprilum (36.7%), Candesartanum (16.3%). The correlation between hemodynamic and antihypertensive modulators: 72.7% had hypervolemia; only 29.7% were treated with diuretics, with statistically signifi cant results [x2=2.79;p=0.09]; patients treated with ACEI/ARBs had hypoinotropism (52.3%)/hyperinotropism (40.9%). 54.5% of patients with beta-blockers had statistically signifi cant results for hypocronotropy [x2=11.35; p=0.001]. Conclusions: Hemodynamic profi le helps identify the causes of uncontrolled hypertension with different classes of antihypertensive drugs. The effect of beta blockers on chronotropism is depending on age and type (selective/non-selective). The effect of thiazide diuretics, associated with a high risk of falls in the elderly, shows the presence of hypervolemia in a small rate, which implies individualized treatment at the elderly, depending on comorbidities and drug interactions.

show abstract

Section: Discussionmentioning

confidence: 99%