Evaluation of the immunomodulatory activity of ethanolic extract of the stem bark ofBauhinia variegataLinn

The antimicrobial, antioxidative, anti-inflammatory activity and cytotoxicity of different fractions of four South African Bauhinia species used traditionally to treat diarrhoea

“…The minimum inhibitory concentration (MIC) for the crude extracts against Staphylococcus aureus (ATCC 29213), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922) and Enterococcus faecalis (ATCC 29212) were evaluated using a serial dilution assay with tetrazolium violet added as a growth indicator Bark, leaves Diarrhoea, infertility (Samie et al, 2010), infertility (Arnold and Gulumian, 1984), amenorrhoea (Van Wyk and Gericke, 2000) Antimutagenic (Reid et al, 2006); antioxidant and cytotoxicity of leaf extracts (Aderogba et al, 2007); anti-campylobacterial, anti-amoebic and cytotoxicity of root bark extract (Samie et al,2009) (Parekh, Chandra, 2007) Anti-inflammatory (Rao et al, 2008); Immune modulator (Ghaisas et al, 2009) kaempferol, ombuin, kaempferol 7,4 0 -dimethyl ether-3-O-b-D-glucopyranoside, kaempferol 3-O-b-D-glucopyranoside, isorhamnetin 3-O-b-D-glucopyranoside, hesperidin, 3-b-trans-(3,4-dihydroxycinnamoyloxy) olean-12-en-28-oic acid (Rao et al, 2008) V¼ Vhavenda, Z ¼ Zulu (Eloff, 1998). The extracts (100 ml) at an initial concentration of 1.0 Â 10 4 mg/ml were serially diluted with distilled water (50%) in 96-well microtitre plates to prepare a concentration range between 5000 and 40 mg/ml in the first well and last well respectively.…”

In-vivo antioxidant and immunomodulatory activity of mesuol isolated from Mesua ferrea L. seed oil

“…The blood samples (25 μl) were then withdrawn from the retro-orbital plexus under mild ether anesthesia at 0 and 15 min after injection of colloidal carbon ink and lysed in 3 ml of 0.1% w/v sodium carbonate solution. The optical density was measured spectrophotometrically at 660 nm [34,37].…”

Acute and 28-Day Repeated Dose Oral Toxicity ofBauhinia variegata(Caesalpiniaceae) Stem Bark Extract

“…Stem bark of B. variegata showed antibacterial (25), hepatoprotective (3), antidiabetic (13), immunomodulatory (9), antiobesity (2), mast cell stabilizing (17), antimutagenic (23), antioxidant, and antihyperlipidemic (26) properties. The aim of the present investigation was to carry out acute and repeated-dose toxicological studies of aqueous extract of B. variegata bark.…”