Evaluation of the Impact of Cognitive Training on Quality of Life in Patients with Multiple Sclerosis

Grasso, Maria Grazia; Broccoli, Marco; Casillo, Paolo; Catani, Sheila; Pace, Luca; Pompa, Alessandra; Rizzi, Francesco; Troisi, Elio

doi:10.1159/000478726

Cited by 17 publications

(11 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, our results suggest that the perception of better cognitive performance in the CG and TG contributed to an improvement in the self-esteem indexes. These findings corroborate the results of other studies on quality of life, depression and anxiety 26 , 27 …”

Section: Discussionsupporting

confidence: 92%

Effect of cognitive stimulation workshops on the self-esteem and cognition of the elderly A pilot project

Schultheisz

Aquino

Alves

et al. 2018

Dement. neuropsychol.

View full text Add to dashboard Cite

According to the WHO, by 2025 Brazil will be ranked sixth in the world in terms of proportion of elderly in the population. Within this scope, cognition plays a central role in the aging process, having an important association with quality of life, which suggests the need to develop intervention programs, such as cognitive training.Objective:To determine the effects of a program of cognitive stimulation workshops on the self-esteem and cognition of elderly people.Methods:Thirty-eight elderly subjects completed the three-step protocol: 1) Survey of demographic data and evaluation of cognition by a neuropsychological battery and of self-esteem using the Rosenberg Self-Esteem Scale (RSS), prior to training; 2) Participation in twelve cognitive stimulation workshops; and 3) Cognitive evaluation and RSS after the training.Results:Results showed that the use of training produced positive effects on cognitive test performance of the elderly with and without cognitive impairment. By extension, this demonstrates positive impact on their self-esteem.Conclusion:These findings encourage investment in cognitive stimulation programs as a resource for improved cognition and quality of life for the elderly. Subjective cognitive complaint may have served as a predictor of decreased self-esteem; therefore, as training improved cognition, it also improved self-esteem.

show abstract

Section: Discussionsupporting

confidence: 92%

Effect of cognitive stimulation workshops on the self-esteem and cognition of the elderly A pilot project

Schultheisz

Aquino

Alves

et al. 2018

Dement. neuropsychol.

View full text Add to dashboard Cite

show abstract

“…The positive association between cognitive rehabilitation and the improved QoL has been previously reported in patients with MS, Parkinson’s disease and brain tumors (Locke et al, 2008; Paris et al, 2011; Mitolo et al, 2015; Grasso et al, 2017). But less is known about the patients who receive CABG surgery, while a large body of evidence reports postoperative cognitive deficits in this group of patients (Shaw et al, 1987; Hammeke and Hastings, 1988; Newman et al, 2001; Bruggemans, 2013; Goto and Maekawa, 2014).…”

Section: Discussionsupporting

confidence: 56%

Efficacy of Neurocognitive Rehabilitation After Coronary Artery Bypass Graft Surgery in Improving Quality of Life: An Interventional Trial

et al. 2019

View full text Add to dashboard Cite

Introduction Cognitive deficits are frequent after coronary artery bypass graft (CABG) surgery and consequently could lead to a decrease in quality of life. This is the first study that has been conducted with the aim of examining the efficacy of a computerized cognitive rehabilitation therapy (CCRT) in improving quality of life in patients after CABG surgery. Methods In this study, an interventional trial with pre-, post-, and follow-up assessments in active (CCRT), active control and control groups was conducted. Seventy-five patients after CABG surgery were selected and assigned to the groups ( n = 25 for each group). CCRT consists of four modules of attention, working memory, response inhibition and processing speed training with graded schedule in 20-min sessions three times per week within 8 weeks. Cognitive functions (attention and working memory) were assessed by the tests of continuous performance, Flanker, useful field of view and digit span at three time points: pre- and post-intervention (T0 and T1) and 6-month follow-up (T2). Quality of life was assessed by the SF-36 questionnaire at the same time points. The CCRT group received the cognitive rehabilitation for 2 months, active control group received a sham version of CCRT in an equal time duration and control group did not receive any cognitive intervention. Results Repeated measures analysis of variance (ANOVA) revealed a time by group interaction on cognitive functions, with CCRT producing a significant improvement at T1 ( p < 0.01) and these improvements were maintained at T2. Moreover, in CCRT and active control groups, quality of life (QoL) improved at T1 and these improvements remained stable throughout follow-up (T2). However, improvement of QoL in CCRT group was greater than improvement of QoL in the other two groups at T1. Pearson’s correlation analysis shows a positive correlation between QoL improvement and sustained attention and working memory enhancement ( p < 0.05). Conclusion Cognitive rehabilitation can lead to a significant improvement in the cognitive functions that have been trained in patients receiving CABG. Interestingly enough, cognitive rehabilitation can also improve quality of life in patients after CABG surgery and this improvement is maintained for at least 6 months.

show abstract

“…The weighted mean Expanded Disability Status Scale score across studies was 3.4 (median = 3.5). In all, 7 studies were from Italy, 28,29,39-43 7 from the United States, 27,44-49 2 from Austria, 50,51 and the others from the United Kingdom, 26 Switzerland, 52 Greece, 53 and Spain. 54 Among the studies, 13 used multidomain training, 4 provided attention training, and active control was confirmed in 11/20 studies.…”

Section: Resultsmentioning

confidence: 99%

Computerized Cognitive Training in Multiple Sclerosis: A Systematic Review and Meta-analysis

Lampit

Heine

Finke

et al. 2019

Neurorehabil Neural Repair

View full text Add to dashboard Cite

Background. Cognitive impairments are common in people with multiple sclerosis (MS). Systematic reviews reported promising evidence for various cognitive interventions in this population. Computerized cognitive training (CCT) has strong evidence for safety and efficacy in several populations, but its effects in MS have yet to be specified. Objective. We aimed to synthesize the evidence from randomized controlled trials (RCTs) investigating the effects of CCT on cognitive, psychosocial, and functional outcomes in adults with MS. Method. We searched MEDLINE, EMBASE, PsycINFO, CINAHL, and CENTRAL from inception to March 2019. We calculated standardized mean difference (Hedges’ g) of change from baseline in untrained measures of cognition, individual domains, psychosocial functioning, and daily function between CCT and control groups using a random-effects model. Results. A total of 20 RCTs encompassing 982 participants (78% with relapsing-remitting MS) were included. The overall cognitive effect size was moderate ( g = 0.30; 95% CI = 0.18-0.43), with no evidence of small-study effect or between-study heterogeneity (prediction interval = 0.17-0.44). Small to moderate effect sizes were found for attention/processing speed, executive functions, and verbal and visuospatial memory. Evidence for working memory, fatigue, and psychosocial and daily functioning were inconclusive. Cognitive effects waned without further training. Conclusions. CCT is efficacious for overall and key cognitive domains in adults with MS, but efficacy on other outcomes and in progressive subtypes remains unclear. Long-term and well-powered trials with diverse cohorts are needed to optimize and maintain the efficacy of CCT, investigate transfer to daily living, and determine who can benefit and whether CCT is a cost-effective strategy to attenuate cognitive decline in MS.

show abstract

Evaluation of the Impact of Cognitive Training on Quality of Life in Patients with Multiple Sclerosis

Cited by 17 publications

References 41 publications

Effect of cognitive stimulation workshops on the self-esteem and cognition of the elderly A pilot project

Effect of cognitive stimulation workshops on the self-esteem and cognition of the elderly A pilot project

Efficacy of Neurocognitive Rehabilitation After Coronary Artery Bypass Graft Surgery in Improving Quality of Life: An Interventional Trial

Computerized Cognitive Training in Multiple Sclerosis: A Systematic Review and Meta-analysis

Contact Info

Product

Resources

About