Evaluation of the Incidence of Discoid Lupus Erythematosus in Patients with Systemic Lupus Erythematosus and Its Relationship to Disease Activity

Abstract

The presence of DLE in our patients with SLE was not associated with less severe disease.

Cutaneous characteristics and association with antinuclear antibodies in 402 patients with different subtypes of lupus erythematosus

“…To date, a total of 180 different antibodies have been detected in SLE patients . In a recent study, the presence of DLE was not associated with systemic disease severity in patients with SLE . In our patients’ group, patients with SLE and CLE correlated significantly more with the prevalence of anti‐U1‐RNP antibodies (38.6% vs. 16.7%, P = 0.0237) and with the consistency of anti‐ds‐DNA antibodies (75.0% vs. 36.8%, P = 0.0163).…”

International multi-center evaluation of a novel chemiluminescence assay for the detection of anti-dsDNA antibodies

“…to define active disease. [28][29][30][31][32][33] Additionally, it is important to point out that the cut-off selection presented by Yee et al 24 underlines the importance of considering the SLEDAI-2K score as a continuous scale, especially in longitudinal studies. Therefore, in this study we also analyzed the relationship of dsDNA positivity by the CIA in relation to the SLEDAI-2K score and found significantly higher scores in the CIA-positive versus the CIA-negative SLE patients (p < 0.0001).…”