Evaluation of the incidence of inflammatory and tumor pathology of nose and nasal sinus region

Nassrallah, Salah; Neagoş, Cristian Mircea; Mocan, Simona; Neagoş, Adriana

doi:10.47162/rjme.61.4.30

Cited by 2 publications

(4 citation statements)

References 14 publications

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“…13 International multicenter studies showed the high risk that nasal polyposis can stimulate nasal and paranasal sinus malignancies. 1 In this patient, chief complaint was nasal congestion on the right side, while on the left nose, which had a polyp, there was no complaint of nasal congestion. In the right nasal cavity, there was an existence of neurofibroma which was a benign lesion originating from neuron cells.…”

Section: Discussionmentioning

confidence: 70%

“…17 Regarding zonal involvement, the literatures revealed that all areas of the nasal cavity and paranasal sinuses could be affected. 1 The anterior part of the nose (nasal vestibule, middle nasal meatus) is common, most of neurofibromas emerge from inferior turbinate or nasal septum, and it could involve the posterior nostril and pharynx. 17 The origin of neurofibroma is considered to be perineural fibroblasts, which originates from neuroectodermal tissue.…”

Section: Discussionmentioning

confidence: 99%

“…Inflammation, and tumor of nasal and paranasal sinuses are a field of great interest in Rhinology worldwide due to its increasing frequency, as well as many aspects related to their etiology, contradictory clinical manifestations, and multitude of therapeutic options. 1 Rhinosinusitis is a common condition globally, leading to a significant burden on society in terms of healthcare costs, and decreasing productivity. 2 Tumors of nose and paranasal sinuses could emerge in any age.…”

Section: Introductionmentioning

confidence: 99%

“…4 Histopathological (HP) examinations is the most important element in tumor diagnosis. 1 Chronic rhinosinusitis (CRS) with nasal polyps as inflammatory disease, along with neurofibroma on nasal cavity as tumor is a rare co-incidence, is there any correlation between these lesions?…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Coincidence of chronic rhinosinusitis with nasal polyps and neurofibroma

Irfandy,

Budiman,

Ikhlas

et al. 2024

Oto Rhino Laryn Indones

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Background: Nasal polyps are painless inflammatory lesions originated from around the middlemeatus or paranasal sinus cavity; while neurofibroma is benign peripheral nerve sheath tumor. Purpose:To report a rare case of neurofibroma concurrently with nasal polyps in chronic rhinosinusitis. Casereport: A 64-year-old female with chief complaint congestion on the right nose cavity. There was a mass on both nasal cavities. Patient diagnosed with benign mass at right nasal cavity and chronic rhinosinusitis with nasal polyps at left nasal cavity; with a differential diagnosis of chronic rhinosinusitis with bilateral nasal polyps. Computer tomography scan results showed homogeneous isodense lesion in the right nasal cavity, and mucosal thickening in left nasal cavity and maxillary sinus. Patient was managed with total extirpation of the bilateral nasal cavity mass and functional endoscopic sinus surgery. Pathological examination revealed neurofibroma in the right nasal cavity and polyps in the left nasal cavity. Clinical question: “How to differentiate inflammation with tumor of nasal and paranasal sinuses? Is there a causal relationship?” Review method: Literature searching was performed with the keywords “nasal cavity neurofibroma”, AND “nasal polyps”, AND ”chronic rhinosinusitis” through database Google Scholar, PubMed, and hand searching/e-book. Result: There were 11 literatures published in the last 5 years, and 7 articles relevant with the subject. Conclusion: Chronic rhinosinusitis with nasal polyps, along with neurofibroma on nasal cavity is a rare co-incidence, and there was no correlation between those lesions. Pathological examination is a gold standard in differentiating a definite diagnosis of neurofibromas and polyps.Keywords: nasal cavity neurofibroma, nasal polyps, chronic rhinosinusitis

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Coincidence of chronic rhinosinusitis with nasal polyps and neurofibroma

Irfandy,

Budiman,

Ikhlas

et al. 2024

Oto Rhino Laryn Indones

View full text Add to dashboard Cite

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Nasal Respiratory Epithelial Adenomatoid Hamartoma: Three Case Reports and Review of the Literature

Liao,

Zhang,

et al. 2023

Ear Nose Throat J

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Hamartomas, as non-true tumors, are commonly found in the lungs, digestive tract, and kidneys, and there are few clinical reports on nasal cases. Nasal histiocytosis accompanied by lymphatic lesions is a common feature of nasal hamartoma. Three patients with nasal cavity hamartoma were treated in our department, including 1 male and 2 females, with nasal obstruction or epistaxis. The imaging (computed tomography, magnetic resonance imaging) of 2 patients showed a soft tissue mass in the nasal cavity and no erosion of bone, while in 1 patient, the imaging was inconclusive. The excised material in all patients was found to be a soft mass. The 3 cases showed the same pattern under histological examination, and all 3 patients were diagnosed with nasal cavity respiratory epithelial adenomatoid hamartoma (REAH). Nasal hamartoma is a rare disease with nonspecific clinical manifestations and imaging features and is often misdiagnosed. Only by a better understanding of this disease can the rate of correct clinical diagnosis be improved.

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Evaluation of the incidence of inflammatory and tumor pathology of nose and nasal sinus region

Cited by 2 publications

References 14 publications

Coincidence of chronic rhinosinusitis with nasal polyps and neurofibroma

Coincidence of chronic rhinosinusitis with nasal polyps and neurofibroma

Nasal Respiratory Epithelial Adenomatoid Hamartoma: Three Case Reports and Review of the Literature

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