In the context of uncertain economic environments urban agglomerations play a crucial role in economic development, reshaping industrial chains and fostering inter-city cooperation. This study employs the Global Production Network (GPN) theory to enhance our understanding of how cities integrate into regions, emphasizing the often-overlooked governmental influence in strategic coupling processes. In examining the evolution of China’s smartphone industry within the Guangdong-Hong Kong-Macao Greater Bay Area (GBA) this research categorizes 19,599 smartphone companies into five distinct groups. Through analyzing their spatial distribution and geographical linkage the study identifies four strategic coupling modes based on the localization of assets, considering spatial influence and technological complexity along horizontal and vertical dimensions. Structural and institutional elements within these modes are also explored. The research uncovers unique integration patterns among nine cities in the GBA’s mobile industry, revealing distinct spatial clusters rooted in technological, resource and innovation factors. Crucially, local policies play a pivotal role. Cities such as Shenzhen and Dongguan emerge as technology hubs, contrasting with Foshan and Zhongshan, which leverage resource advantages. The spatial impact, contingent on specific assets, underscores the necessity for nuanced top-down coupling methods in regional development. Moreover, the study emphasizes the significance of nurturing innovation links, not only between leading companies but also among midstream and downstream enterprises, enhancing cities’ strategic coupling capabilities.