2012
DOI: 10.1016/j.vetimm.2012.06.020
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Evaluation of the interferon-gamma (IFN-γ) assay to diagnose Mycobacterium bovis infection in pigs

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Cited by 18 publications
(14 citation statements)
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“…Thus, the IFN-␥ assay yielded a sensitivity of 100%. Despite that, this sensitivity was higher than the one reported for freerange domestic pigs in Italy, which was 79 to 85% (23); however, the conditions of the two studies are different, i.e., controlled laboratory versus field conditions. It is also important to note that all pigs tested negative to IFN-␥ at T2 (i.e., prior to challenge).…”
Section: Discussioncontrasting
confidence: 63%
See 1 more Smart Citation
“…Thus, the IFN-␥ assay yielded a sensitivity of 100%. Despite that, this sensitivity was higher than the one reported for freerange domestic pigs in Italy, which was 79 to 85% (23); however, the conditions of the two studies are different, i.e., controlled laboratory versus field conditions. It is also important to note that all pigs tested negative to IFN-␥ at T2 (i.e., prior to challenge).…”
Section: Discussioncontrasting
confidence: 63%
“…In pigs, tests based on cell-mediated immunity are commonly used in some countries (e.g., Italy [23]). However, antibody detection by ELISA and/or immunochromatographic tests is not frequent in pigs.…”
mentioning
confidence: 99%
“…The prevalence of M. bovis infection in pigs has declined sharply in countries with effective bovine tuberculosis control in cattle, supporting the assumption that they are dead-end hosts (Cousins 2001;Pesciaroli et al 2012). Exceptions to this trend are reported from developing countries.…”
Section: Mycobacterium Bovis Infections At the Animal/ Human Interfacementioning
confidence: 84%
“…The study, however, highlighted the difficulties related to the restraint of the animals that make this test scarcely applicable to the routine bTB testing in the field. Conversely, in a previous study (10), our group already tested IGRA performances on pigs. The study showed that IGRA is an easy-to-apply test, requiring just a blood sampling, and suggested the possible large-scale use of IGRA in pigs, due to the high diagnostic power and the reliable accuracy (10).…”
Section: Introductionmentioning
confidence: 99%