Evaluation of the ions release / incorporation of the prototype S-PRG filler-containing endodontic sealer

Abstract

Objective: This study aimed to evaluate a prototype surface reaction-type pre-reacted glass-ionomer (S-PRG) filler-containing endodontic sealer (S-PRG sealer) in terms of its ion-releasing ability and the incorporation of the released ions by root canal dentin. Materials and Methods: The concentration of ions in the set S-PRG sealer was measured by ICPS and with a fluoride ion electrode. Element mapping and chemical component bulk analysis of the outermost dentin of the S-PRG sealer-dentin interface were performed by SEM-EPMA. The incorporation depth of the elements in dentin was measured by element line scanning. Results and Discussion: Ions released from the S-PRG sealer (Al, B, F, Na, Si, Sr, and Zn) were detected over time. The incorporation of fluoride (F), strontium (Sr), silicon (Si), and boron (B) was observed along the outermost dentin of the S-PRG sealer-dentin interface by EPMA analysis, and the incorporation depth increased with prolonged immersion. Conclusion: The continuous release of ions from the S-PRG sealer and their subsequent incorporation by root canal dentin were confirmed.

Evaluation of selected properties of a new root repair cement containing surface pre-reacted glass ionomer fillers

“…Our study demonstrated that S-PRG released 6 different types of ions throughout all tested time points, which is consistent with previous studies conducted on various S-PRG based materials [16,41]. In addition to the expected antibacterial action of some of the ions released 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 15 by S-PRG, ions like fluoride and strontium may play an important role in apatite formation and stability.…”

“…It is the most reliable mechanical test that can rank the dislodgment resistance of various endodontic materials applied to dentine such as root canal sealers, root repair materials and intraradicular posts 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 study (7 days), which was selected because it is the common storage time used in the vast majority of studies investigating the push-out bond strength of calcium silicate root cements [25,56]. Fluoride, strontium and silicon ions released from a prototype S-PRG-based root canal sealer were suggested to incorporate into root dentine significantly deeper after one and three months of application compared to one week application [41]. The bond strength of MTA at the apical part of the roots showed a severe and significant drop compared to other locations.…”

Evaluation of the ion-releasing and recharging abilities of a resin-based fissure sealant containing S-PRG filler

“…A recently published study reported that Sr enhances enamel remineralization when used in conjunction with fluoride 28) . Moreover, B, F, and Sr ions released from S-PRG filler may have antibacterial activity 29) , but further analysis of these properties needs to be performed. Cattani-Lorente et al reported that Na is present in the S-PRG filler composition and is released with Al 30) .…”

The effect of multi-ion releasing filler contents on the dentin bond strength of an adhesive resin developed for direct pulp-capping

“…Several studies have provided evidence indicating that S-PRG fillers release Al, B, F, Na, Si, and Sr ions [8][9][10][11][12][13] . Further, it has been reported that Si, Sr, and F ions released from S-PRG fillers are effective in improving the acid resistance of tooth surfaces [18][19][20][21]35) .…”

“…S-PRG fillers release aluminium (Al), boron (B), fluoride (F), sodium (Na), silicon (Si), and strontium (Sr) ions [8][9][10][11][12][13] . Si and F ions are known as strong inducers of remineralization of the dentin matrix [14][15][16][17] .…”