“…87,88 [ 11 C]MET-uptake correlates to cell proliferation in vitro, the expression of Ki-67 and proliferating cell nuclear antigen, as well as to microvessel density, explaining its role as a marker for active tumor proliferation. 82,89,90 The intensity of [ 11 C]METuptake differentiates between WHO II°and WHO III°/ IV°gliomas (FIG. 3).…”