Evaluation of the newcastle disease antibody level after vaccination regimes in chickens in Debrezeit Agricultural Research Center, Ethiopia

Abstract

Evaluation of the Newcastle disease (NCD) antibody level after different vaccination regime was conducted on 110 chickens: (32%) vaccinated and kept separated, (25.2%) unvaccinated and kept with vaccinated, (25.2%) were control groups. Four vaccination regime of chicken against NCD using live lentogenic stain, Hithcner B1 (at the age of 3 day old) and lasota (at the age of 27, 63, and 112th days of age) were used. The overall antibody level of ND in examined chickens using HI test was Log 2 4.42 in unvaccinated and mixed with vaccinated birds, Log 2 5.2 in vaccinated and mixed with unvaccinated chickens, Log 2 2.6 in control groups and Log 2 5.3 in vaccinated and kept separately. On the other hand chickens vaccinated four times at 3, 27, 63 and 112 days were found to be protective as that of common vaccination schedule (0, 18, 72, 132 and 216 day old age) in antibody level of Newcastle disease among different vaccination regime and frequencies. The result of the present study indicated that the protective antibody titter response was produced from the vaccination; hence, it is very crucial to vaccinate chickens with the full dose of vaccines against NCD in order to keep protected poultry population.

Evaluation of the immune response of layer chickens to Newcastle disease virus vaccines using the new vaccination regimens

“…Compared to the standard schedule used in Ethiopia, this approach provided superior protection against the virulent ND virus, enhancing layer chicken immunity through eye-administered live virus vaccines. Anebo et al (2014) reported similar findings, stating that the new immunization method provided protective immunity that was comparable to the conventional approaches employed in Ethiopia.…”

“…Anebo et al. (2014) reported similar findings, stating that the new immunization method provided protective immunity that was comparable to the conventional approaches employed in Ethiopia. Furthermore, several studies (Kapczynski et al., 2013; Sedeik et al., 2019; Sedeik et al., 2022) have suggested that vaccination programs employing a progressive strategy, which involves successive booster immunizations with increasingly virulent strains, could offer protection against clinical disease and mortality following infection with virulent NDV.…”

“…Poultry farming plays a vital role in providing sustenance and income for communities worldwide, particularly in low‐ and middle‐income countries where rural households rear a substantial 70% of all chickens (Mujyambere et al., 2022). However, challenges arise in the form of the Newcastle disease (ND), a pervasive threat that significantly impacts chicken populations, leading to high mortality rates during severe outbreaks (Anebo et al., 2014). This disease, a major cause of bird mortality globally, poses a particularly severe risk to chickens, especially in regions like Ethiopia, where it is colloquially known as ‘Yedoro Fengil,’ highlighting its sudden onset and severity (Tulu, 2020; Asfaw et al., 2021).…”

Determination of Immune Response Traits in Nigerian Indigenous Chickens Challenged with Newcastle Inactive Antigen

“…Newcastle disease is a highly contagious and commonly fatal viral poultry disease affecting domesticated and wild avian species 4 . The disease affects birds of all ages.…”

Newcastle disease and its different applicable control options in poultry in Ethiopia

“…However, chicken production is constrained by the disease, predation, lack of management and appropriate breeds in the country (Tadiose et al, 2016); (Terfa et al, 2018)). Among these constraints, disease is the most important and responsible for reducing both numbers and productivity, mortality from egg to adult because of the disease can be estimated to be 80% during some spectacular epidemics (Kinung'hi et al, 2004); Zelalem et al (2014). Different poultry disease has been reported in Ethiopia, the major cause of economic losses being Newcastle disease (ND), coccidiosis, chronic respiratory disease, Marek's disease, Nutritional deficiencies (Lobago et al, 2005;Mesfin and Bihonegn, 2018).…”