Evaluation of the Outcome of Patients Admitted to the Pediatric Intensive Care Unit in Tripoli Using the Pediatric Risk of Mortality (PRISM) Score

Elhadi, Muhammed; Esahli, Hamida; Ahmed, Hazem A. Sayed; Ittire, S.; Dougman, K.; Khalil, Mounir; Ali, Aliya Miftah; Khaled, Ala; Sadouh, Enas Ahmed; Abugrin, Mohamed; Elhadi, Ahmed

doi:10.1542/peds.144.2ma4.379

Cited by 3 publications

(3 citation statements)

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“…[20][21][22] However, it was lower than other studies in the United States (14.5%), India (16.7%), Taiwan (22%), Pakistan, and Turkey (12.9-18%). 6,18,[23][24][25] The differences in these mortality rates can be due to population age range, diagnosis, and PICU environment.…”

Section: Discussionmentioning

confidence: 99%

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Karakaya

Boyraz

Atis

et al. 2023

J Pediatr Intensive Care

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The objective of this study was to identify the characteristics of nonsurvivors in a pediatric intensive care unit (PICU) in Turkey. This is a retrospective analysis of patients who died in a tertiary PICU over a 6-year period from 2016 to 2021. Data were drawn from electronic medical records and resuscitation notes. Mode of death was categorized as failed cardiopulmonary resuscitation (F-CPR) or brain death. Among the 161 deaths, 136 nonsurvivors were included and 30.1% were younger than 1 year. Severe pneumonia, respiratory failure, and acute respiratory distress syndrome (ARDS) (31.6%) were the most common primary diagnoses. The most common mode of death was F-CPR (86.8%). More than half of the subjects had been admitted from pediatric emergency departments (58.1%), and more than half (53.7%) had died within 7 days in the PICU. Patients admitted from pediatric emergency departments had the lowest frequency of comorbidities (p < 0.001). Severe pneumonia, respiratory failure, and ARDS diagnoses were significantly more frequent in those who died after 7 days (p < 0.001), whereas septicemia, shock, and multiple organ dysfunction were more common among those who died within the first day of PICU admission (p < 0.001). It may be important to note that patients referred from wards are highly likely to have comorbidities, while those referred from pediatric emergency departments may be relatively younger. Additionally, patients with septicemia, shock, or multiple organ dysfunction were more likely to die earlier (within 7 days), especially compared with those with severe pneumonia, respiratory failure, or ARDS.

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Section: Discussionmentioning

confidence: 99%

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Karakaya

Boyraz

Atis

et al. 2023

J Pediatr Intensive Care

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“…21 Study conducted by Costa et al showed PRISM score showed adequate discriminatory capacity and calibration and thus constitutes a useful gizmo for the assessment of prognosis for paediatric patients admitted to a tertiary PICU with a median value of 15 in deaths and ROC curve yielded a value of 0.76 (CI 95% 0.69-0.83) p<0.0001 whereas our study showed a median value of slightly higher of 21 and acceptable discriminatory capacity and calibration for the assessment of prognosis in PICU patients (p<0.0001) and showed satisfactory discriminatory performance in differentiating survivors from non-survivors, supporting the conclusion that higher PRISM scores are correlated with increased risk of death, similar other studies. [22][23][24][25][26][27] Martha et al evaluated the PRISM scores of 421 patients and showed good discriminatory performance with proper calibration. 23 Brakel et al and Leuteurtre et al showed that the PRISM score provides good discriminatory power for patients with meningococcal disease and in children with meningococcal septic shock.…”

Section: Discussionmentioning

confidence: 99%

Prognostic significance of serum pro-calcitonin level in paediatric intensive care unit patients

Kumar¹,

Kumar

Belagodu³

et al. 2023

Int J Contemp Pediatr

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Background: Serum procalcitonin (PCT) is already known predictive marker in serious bacterial infection and it is emphasized that these biomarkers can be used as a marker of increased mortality in critically ill patients. The aim of the study was to evaluate the serial PCT level and find out whether these biomarkers can be used to predict mortality. Methods: This was a prospective observational study. Primary objective was to study the serum PCT as a prognostic marker in critically ill children (2 months to 12 years) admitted in PICU while secondary objective was to find out the association of level of serum procalcitonin with different organ system disease involvement and to compare the results of the serum procalcitonin with the PRISM-3 score in diagnosing the severity of illness in the patient. Patient outcome was assessed at hospital discharge, and the patients were divided into non-survivors and survivors. A p value of <0.05 will be considered statistically significant. Results: A total of 185 patients were enrolled, the median age was 5 years (2 months to 12 years) with 56.76% being males. Majority (34.59%) of patients the primary diagnosis was of respiratory system. The median of serum PCT on day 1, day 3 and day 7 with outcome (p<0.05) in dead was significantly higher as compared to alive. The median PRISM score in dead was 21(13-33) which was significantly higher as compared to alive 11 (8-12.7). Serum PCT and PRISM score had significant discriminatory power to predict mortality. Conclusions: In the present study serum PCT found to be a good prognostic marker for all cause mortality in critically ill patients admitted in PICU.

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“…The PRISM score is just one of the many parameters studied for the assessment of mortality among patients, and it is not the exact evaluating parameter to predict outcomes in a particular nutritional condition of critically ill children. It focuses on relevant physiological values such as weight for age and other such factors that predict outcomes such as LOS and mortality [8]. As a proposed effort, combining nutritional status with the PRISM score can be a more efficient approach to the prediction of outcomes such as mortality.…”

Section: Pediatric Risk Of Mortality (Prism) Score and Malnutritionmentioning

confidence: 99%

Impact of malnutrition on the outcome of critically-ill children: A comprehensive narrative review

Agrawal,

Agrawal

2024

Indian J Child Health

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Malnutrition presents a universal challenge, affecting millions of children and resulting in severe health consequences. Notably, its consequences within the pediatric population, especially those that necessitate admission to the pediatric intensive care unit (PICU), are of concern. This narrative review discusses the nutritional status, particularly malnutrition, and factors associated that impact the outcome during the PICU stay. Furthermore, the interpretation of clinical conditions and physiological aspects and the understanding of potential interventions together help to analyze the outcome associated with malnutrition. By studying these aspects, this review proposes to contribute a proper understanding of how malnutrition closely influences outcomes in the condition of children admitted to PICUs.

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Evaluation of the Outcome of Patients Admitted to the Pediatric Intensive Care Unit in Tripoli Using the Pediatric Risk of Mortality (PRISM) Score

Cited by 3 publications

References 0 publications

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Descriptive and Clinical Characteristics of Nonsurvivors in a Tertiary Pediatric Intensive Care Unit in Turkey: 6 Years of Experience

Prognostic significance of serum pro-calcitonin level in paediatric intensive care unit patients

Impact of malnutrition on the outcome of critically-ill children: A comprehensive narrative review

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