Evaluation of the Quality of Codonopsis Radix in Different Growth Years by the AHP‐CRITIC Method

Wang, Yanping; Wang, Zixia; Zhang, Jingjing; Yu, Huaqiao; Chen, Yan; Gao, Yingrui; Li, Xiaodong; Li, Wen; Hu, Fangdi

doi:10.1002/cbdv.202201108

Cited by 8 publications

(4 citation statements)

References 29 publications

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“…In contrast, CP produced in Weining County may be associated with neuroprotection and cardiovascular system improvement ( Zhang et al, 2023 ). In addition, climatic conditions, altitude, topography, growth environment and growth years may affect CP growth and quality ( Fan L. et al, 2023 ; Wang et al, 2023 ). Meanwhile, different extraction conditions and methods may also significantly affect the purity and proportion of CP active ingredients ( Luan et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

A systematic review of the mechanism of action and potential medicinal value of codonopsis pilosula in diseases

Guo,

Lou,

Hou

et al. 2024

Front. Pharmacol.

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As a traditional Chinese medicinal herb with a long history, Codonopsis pilosula (CP) has attracted much attention from the medical community in recent years. This review summarizes the research progress of CP in the medical field in the past 5 years. By searching and analyzing the literature, and combining with Cytoscape software, we comprehensively examined the role and mechanism of action of CP in individual application, combination drug application, and the role and mechanism of action of codonopsis pilosula’s active ingredients in a variety of diseases. It also analyzes the medicinal use of CP and its application value in medicine. This review found that CP mainly manifests important roles in several diseases, such as cardiovascular system, nervous system, digestive system, immune system, etc., and regulates the development of many diseases mainly through the mechanisms of inflammation regulation, oxidative stress, immunomodulation and apoptosis. Its rich pharmacological activities and diverse medicinal effects endow CP with broad prospects and application values. This review provides valuable reference and guidance for the further development of CP in traditional Chinese medicine.

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Section: Discussionmentioning

confidence: 99%

A systematic review of the mechanism of action and potential medicinal value of codonopsis pilosula in diseases

Guo,

Lou,

Hou

et al. 2024

Front. Pharmacol.

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“…The weight coefficients of these indicators were calculated using the AHP‐CRITIC method. The AHP‐CRITIC method overcomes the drawbacks of separate calculations and is a more scientifically rigorous approach for determining weight coefficients 26 . This process facilitated the selection of the optimal extraction method.…”

Section: Methodsmentioning

confidence: 99%

“…The AHP-CRITIC method overcomes the drawbacks of separate calculations and is a more scientifically rigorous approach for determining weight coefficients. 26 This process facilitated the selection of the optimal extraction method. In this experiment, the optimal conditions were identified by investigating three factors: the effect of the amount of water added (the ratio of solvent volume to material weight, factor A), extraction duration (factor B), and extraction repetitions (factor C).…”

Section: Determination Of Optimal Extraction Process Via the Ahp-crit...mentioning

confidence: 99%

Optimization of the Zhou Tian Formula extraction technology based on AHP‐CRITIC method and analysis of transfer efficiency of key components based on HPLC fingerprinting

Ma,

Feng,

Yao

et al. 2024

Phytochemical Analysis

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IntroductionZhou Tian Formula (ZTF) is an antidepressant traditional Chinese medicine utilized widely in clinical settings for the treatment of patients with depression. However, shortcomings persist in its extraction technology and quality control.ObjectiveThis study aimed to propose a methodology for ZTF extraction technology based on the analytic hierarchy process (AHP)–criteria importance through intercriteria correlation (CRITIC) method and to establish a quality control framework for the efficient transfer of index components.MethodFirstly, we analyzed the chemical components of ZTF and determined the optimal extraction technology. Secondly, we calculated the transfer efficiency of the index components during the conversion of water decoction to extract powder and subsequently to granules. Thirdly, we established HPLC fingerprints for 15 batches of ZTF water decoction, extract powder, and granules. We employed SIMCA software to analyze the chemicals responsible for variations in quality among different batches of ZTF granules.ResultsWe determined the optimal extraction process. The average transfer efficiency of ferulic acid, puerarin, mirificin, isoferulic acid, and calycosin during the conversion of water decoction to extract powder and subsequently to granules exceeded 41%. The HPLC fingerprints of ZTF exhibited a similarity exceeding 0.890. Variable importance in projection values indicated that calycosin, ferulic acid, and puerarin were the primary contributors to quality variations.ConclusionsThe AHP‐CRITIC method, coupled with an orthogonal array design, could be used for exploring extraction technology. In addition, the rules governing the transfer of index components from water decoction to extract powder, and subsequently to granules, could be applied for the evaluation and quality assessment of ZTF.

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“…The elution condition of syringin was described according to Wang et al [25]. The mobile phase consisted of acetonitrile (A)-water (B) with gradient elution.…”

Section: Lobetyolin Content Syringin Content and Atractylenolide III ...mentioning

confidence: 99%

Exploration of Postharvest Conditions for Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen Roots Based on Sensory Quality, Active Components, Antioxidant Capacity and Physiological Changes at Different Storage Temperatures

Wen,

Wang,

Song

et al. 2023

Foods

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The promotion of industrial-mode production of Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen (C. pilosula) has expanded the demand for the postharvest storage of fresh roots. Further research is needed to establish comprehensive methods to evaluate the impact of storage conditions. This study simulated the storage process of roots at near-freezing temperature [NFT (−1 °C)] and traditional low temperatures (−6 °C, 4 °C and 9 °C) for 40 days. At different storage stages, correlation analysis was conducted using quantitative data on 20 parameters, including sensory quality, active components, antioxidant capacity and physiological changes. Appearance and principal component analysis could distinguish between fresh and stored samples, while NFT samples on the 40th day of storage were similar to fresh ones. Correlation analysis indicated that NFT storage could maintain the sensory quality by increasing the antioxidant enzyme activity and active components, reducing the accumulation of reactive oxygen species and malondialdehyde and reducing the activity of browning-related enzymes and cell-wall-degrading enzymes. These findings highlight the importance of the overall quality evaluation of fresh roots and emphasize the potential to improve fresh root and dried medicinal material quality by regulating storage conditions such as temperature.

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Evaluation of the Quality of Codonopsis Radix in Different Growth Years by the AHP‐CRITIC Method

Cited by 8 publications

References 29 publications

A systematic review of the mechanism of action and potential medicinal value of codonopsis pilosula in diseases

A systematic review of the mechanism of action and potential medicinal value of codonopsis pilosula in diseases

Optimization of the Zhou Tian Formula extraction technology based on AHP‐CRITIC method and analysis of transfer efficiency of key components based on HPLC fingerprinting

Exploration of Postharvest Conditions for Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen Roots Based on Sensory Quality, Active Components, Antioxidant Capacity and Physiological Changes at Different Storage Temperatures

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