Evaluation of the Relationships between Corneal Parameters, Ocular Biometry, and Myopia Magnitude

Hairol, Mohd Izzuddin; Arif, Norlaili; Yong, Pui Theng; Ali, Mariah Asem Shehadeh Saleh; Idris, Nik Nor Adlina Nik; Ng, Li Ching

doi:10.17576/jsm-2021-5010-20

Cited by 2 publications

(2 citation statements)

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“…As far as we know, studies have only focused on the relationship between CCT and refractive errors, and the relationship between CV and refractive errors was absent until now. Previous studies have reported that CCT was not significantly associated with refractive errors 20,21 and demonstrated that CCT was highly inherited 22 . Heritability studies conducted in twins and family members indicated that CCT is one of the most highly heritable human traits 23,24 .…”

Section: Discussionmentioning

confidence: 94%

The distribution pattern of corneal volume in Chinese myopic patients from multiple centers

Tang

Qin

Wang

et al. 2023

MedComm – Future Medicine

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Corneal volume (CV) is a useful index for detecting forme fruste keratoconus from normal corneas. It can be used to evaluate the whole cornea, since it can measure corneal areas up to 10 mm in diameter. Thus, CV has become the clinicians' interest as a diagnostic tool of corneal ectatic disease and a measure of corneal integrity to determine suitability for refractive surgery. We conducted a cross‐sectional study including 7893 myopic patients from five ophthalmic centers to investigate the distribution pattern of CV. Our study showed that distribution of CV‐3, CV‐5, and CV‐7 mm were slightly positively skewed and the 2.5th to 97.5th percentiles were 3.6–4.4, 10.4–12.8, 22.5–27.5 mm3, respectively. Central corneal thickness (CCT) was significantly correlated with CV in all measurement regions. The correlation between CV and CCT showed an inconsistent trend with the increase of age. The correlation coefficient between CV and CCT did not change significantly with the increase of myopia degree in low to moderate myopia, but fluctuated significantly in high myopia (less than −6.0 diopters). According to our results, corneal volume follows a slightly positively skewed distribution pattern in myopic Chinese patients. The information is useful for screening refractive surgery candidates and assessing the risk of corneal refractive surgery.

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Section: Discussionmentioning

confidence: 94%

The distribution pattern of corneal volume in Chinese myopic patients from multiple centers

Tang

Qin

Wang

et al. 2023

MedComm – Future Medicine

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“…A recent study by Hairol et al . [ 16 ] reported that corneal curvature correlated significantly with axial length (P=0.001) but not with myopia magnitude (P=0.91). They concluded that myopia magnitude and axial length are more sensitive to detecting changes in corneal curvature in myopes.…”

Section: Introductionmentioning

confidence: 99%

Morphology and thickness of corneal endothelial cells in young Sudanese individuals with myopia

Mutwaly,

Alrasheed,

Elmadina

et al. 2023

JMedLife

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Deviations in corneal endothelium morphology and thickness may indicate corneal abnormalities and could be associated with myopia development. This study aimed to evaluate corneal endothelial cell morphology and central corneal thickness in young individuals with myopia. A prospective study was conducted at Al-Neelain University Eye Hospital between January 2019 and January 2020, including 160 patients with myopia (320 eyes). Data was gathered through clinical assessment of visual acuity, refractive error, and corneal endothelial cells. Results showed that 60% of participants with myopia were female, with a mean age of 21.99±2.8 years and a mean equivalent sphere of -3.19±2.67D. There was a significant difference in endothelial cell degeneration between myopia groups (P<0.001). Corneal guttata occurred in 9.1% of eyes with low myopia and 68.2% with moderate myopia, whereas polymegathism and polymorphism were more prevalent in high myopia. The mean central corneal thickness was 500.50±38.94 µm in low myopia, 497.02±36.23 µm in moderate myopia, and 477.87±43.625 µm in high myopia (P=0.007). The mean endothelial cell number in low myopia was 107.86±21.12, 106.0±24.03 in moderate myopia, and 101.23±18.49 in high myopia (P<0.05). The mean difference in endothelial cell density, coefficient of variation, and hexagonality in low, moderate, and high myopia was not significant (P>0.05). However, Pearson’s correlation revealed a significant negative correlation between the degree of myopia and central corneal thickness (r= -0.174, P=0.002) as well as endothelial cell number (r= -0.124, P=0.026). The study concluded that central corneal thickness and endothelial cell number significantly decreased with an increase in the degree of myopia. Corneal guttata was the most common form of endothelial cell degeneration observed in cases of high myopia.

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Evaluation of the Relationships between Corneal Parameters, Ocular Biometry, and Myopia Magnitude

Cited by 2 publications

References 0 publications

The distribution pattern of corneal volume in Chinese myopic patients from multiple centers

The distribution pattern of corneal volume in Chinese myopic patients from multiple centers

Morphology and thickness of corneal endothelial cells in young Sudanese individuals with myopia

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