Evaluation of the Salivary Flow Rate and pH in Patients with Recurrent Oral Ulcers

Abstract

Introductions: Recurrent oral ulcers primarily effect mucosal surfaces and are among the most common chronic inflammatory diseases. Numerous studies to find the aetiopathogenesis have been conducted however the cause still remains unclear. Saliva is of utmostimportance for oral health maintenance. In current study, saliva was used as a diagnostic tool for comparison of salivary flow rate and pH in patients suffering from recurrent oral ulcers and control group. Materials and Methods: Saliva samples taken from 20 recurrent aphthous ulcer patients and 20 control (healthy) patients using a convient sampling method. Drooling method was used to collect unstimulated whole saliva sample. Pre-weighted specimen bottles were used and then weighed after sample collection on a graduated scale where as chair-side pH meter was used to determine the salivary pH. Independent t-test and Pearson’s correlation were performed. A p-value of less than 0.05 was considered statistically significance. Results: Positive correlation was found between the flow rate and pH in recurrent oral ulcer patients. Patients with recurrent oral ulcers had higher flow rate and pH compared to the control group. These effects were exaggerated in female patients with ulcers. Conclusions: Disturbances in salivary flow rate and pH were not significantly associated with recurrent oral ulcers.

Dental erosion following clopidogrel administration in a dog: A case‐based study

“…Studies have shown that dog saliva is more alkaline than human saliva; therefore, it may have a higher buffering capacity for acids (Al‐Ahmad et al., 2018 ; Lavy et al., 2012 ). The lack of reports on significant enamel loss in dogs treated with clopidogrel is attributed to the buffering ability of saliva.…”

“…Dental erosion refers to the loss of enamel due to acquired causes, and the most prominent etiological factor in humans is known to be low pH (Barbour et al., 2011 ). Dog saliva has a pH of 8.5, making it more alkaline and resulting in a higher buffering capacity compared to human saliva (pH 6.2–7.6) (Al‐ahmad et al., 2018 ; Lavy et al., 2012 ). This difference in saliva composition between humans and dogs is thought to be the reason why caries or erosion are less common in dogs (Pasha et al., 2018 ).…”

pH analysis of still and carbonated bottled water: Potential influence on dental erosion

“…In healthy individuals, the pH of saliva varies between 6.20 and 7.60 (Al et al, 2018 ) and is maintained at a non‐harmful level to the oral cavity through three buffer systems (bicarbonate, phosphate, and protein) (Dawes et al, 2015 ), depending and being strongly associated with the salivary secretion flow (Aframian et al, 2006 ).…”