Evaluation of the Saxon test for patients with hyposalivation without Sjögren’s syndrome

Minagi, Hitomi Ono; Yamanaka, Yoshie; Sakai, Takayoshi

doi:10.1111/joor.13093

Cited by 10 publications

(8 citation statements)

References 20 publications

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“…Using multiple regression analysis, we examined the factors affecting the Saxon test score for patients. Our results showed that age and sex significantly affected the Saxon test score; this data showed as same as the past study results [8]. The elderly patients showed harder hyposalivation than young patients except the factor of the medication.…”

Section: Discussion/conclusionsupporting

confidence: 91%

“…For drug-induced xerostomia, using the lowest effective dose or switching to an alternative medication may help. However, there are few considerations regarding the underlying situation and the patients' intake of medicines for xerostomia [7,8]. Xerostomia is a common complaint observed in the elderly who often complain of oral dryness as a result of underlying diseases and as a side effect of taking drugs [9].…”

Section: Introductionmentioning

confidence: 99%

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Analysis of medication-induced xerostomia in elderly Japanese patients

et al. 2021

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Objectives To determine the general condition of elderly xerostomia patients, we collected their background and medication data in order to potentially treat their xerostomia. It is critical to identify the drugs causing xerostomia in elderly patients. A total of 521 patients who were examined at the Xerostomia Clinic of Osaka University Dental Hospital were included in the study. We obtained patients’ data on age, sex, number of primary illnesses, Saxon test scores, oral moisture test, subjective symptoms, and drug types from their clinical records. Results The mean age of the patients was 65.2 ± 13.3 years. Although all patients exhibited xerostomia symptoms, there were a lot of patients without hyposalivation. With respect to medication, each elderly xerostomia patient took an average of 6.8 ± 4.4 medicines. A total of 26.1% of patients in their 70 s took more than ten number of drugs. In addition, the number of frequently used medication medicine was different between elderly and young patients. Most of the medicines had xerostomia as a side effect in medical package inserts. Moreover, the quantity of salivation significantly decreased in patients who took more than seven drugs in comparison with the patients who did not take medicine. Conclusions As patients age, the number of medications they take tends to increase, subsequently increasing their risk of xerostomia. For the health of the patients, it is critical that an accurate diagnosis is made. Clinical relevance To establish therapeutic strategies for treatment of xerostomia, this study provides new and important information that will help in the development of xerostomia medical treatment.

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Section: Discussion/conclusionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Analysis of medication-induced xerostomia in elderly Japanese patients

et al. 2021

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“…The moisture levels of the oral mucosa were measured using an oral moisture-checking device (Mucus®, LIFE Co.). The device analyzes water maintenance of the mucous membrane 13 . The oral moisture score of the buccal mucosa was repeated thrice, and the median value was selected.…”

Section: Opportunistic Bacterial Count Measurementmentioning

confidence: 99%

Examination of oral care using MA-T gel for high-risk patients – A pilot study

Minagi

Gojo

Nohno

et al. 2022

Preprint

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To prevent aspiration, oral care with gel is a common method for high-risk patients. An oral care gel is used to clean and moisturize the oral cavity. However, the effects of gel care on oral bacteria remain unclear. In this pilot study, we describe a matching transformation system (MA-T) for elderly high-risk patients. MA-T is an on-demand aqueous chlorine dioxide solution that provides excellent safety with various antimicrobial activities even in the presence of abundant organic compounds. This study investigated the effects of MA-T gel on patients requiring nursing care. Membranous substances were present in the oral cavities of all patients. Oral bacteria and intraoral humidity were examined by daily care using an MA-T gel. Moreover, oral membranous substances were analyzed and bacteria were cultured in selective mediums for opportunistic infection. Consequently, the number of bacteria decreased and oral moisture was improved by treatment with MA-T gel. It is important to care for MA-T gels not only for the single use of professional care but also for daily care. Furthermore, culture experiments showed that MA-T controlled the propagation of opportunistic bacterial infections. The MA-T gel proved to be effective for the oral care of elderly people. Membranous substances may be observed in the oral cavity of persons requiring nursing care for tubal feeding. The results of this pilot study suggest that MA-T, a new disinfectant, can be applied in oral care to reduce aspiration.

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“…In typical clinical practice, in addition to the distinct signs of dry mouth (which Jager et al simplified into a clinical oral dryness score [ 6 ] for rapid screening), various quantitative tests of salivary excretion have been proposed to evaluate dry mouth and can be divided into the following five categories, as reported by Löfgren et al [ 7 ]: Secretion tests, including sialometry, the oral Schirmer’s test [ 8 ], the Saxon test [ 9 ], and methods that explores changes in salivary composition [ 10 ]; Mucosal/surface tests such as measurements of mucosal saliva thickness [ 11 ] or salivary smears [ 12 ], or measurements of the impedance of oral mucosa on a moisture-checking device [ 13 ]; “Functional” tests performed by using the dissolution of candy [ 14 ] or wafers [ 15 ]; Glandular morphology, including sonography [ 16 ], magnetic resonance imaging (MRI) [ 17 ], sialography, and salivary gland scintigraphy (sialoscintigraphy); Questionnaires, interviews, or a combination of both [ 18 ]. …”

Section: Introductionmentioning

confidence: 99%

“…Secretion tests, including sialometry, the oral Schirmer’s test [ 8 ], the Saxon test [ 9 ], and methods that explores changes in salivary composition [ 10 ];…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Salivary Scintigraphic Evaluation of Salivary Gland Function

Chen

Hsu

2021

Diagnostics

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Saliva plays an important role in supporting upper gastrointestinal tract function and oral well-being. Salivary dysfunction mainly manifests with a decrease in salivary flow. Among varieties of quantitative methods, salivary scintigraphy is a relatively noninvasive, well-tolerated, reproducible, and objective approach for functional evaluation of salivary disorders, yet the lack of precise quantitative reference values and no standardized protocol limit its generalized utilization. In this article, we review the scintigraphic performance between the visual analysis and quantitative methods in predicting Sjögren’s syndrome and verify the potential aspects of the application in interpreting different disease entities and phases of functional salivary disorders.

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Evaluation of the Saxon test for patients with hyposalivation without Sjögren’s syndrome

Cited by 10 publications

References 20 publications

Analysis of medication-induced xerostomia in elderly Japanese patients

Analysis of medication-induced xerostomia in elderly Japanese patients

Examination of oral care using MA-T gel for high-risk patients – A pilot study

Recent Advances in Salivary Scintigraphic Evaluation of Salivary Gland Function

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