Evaluation of the Shear Bond Strength and Antibacterial Activity of Orthodontic Adhesive Containing Silver Nanoparticle, an In-Vitro Study

Abstract

This study evaluated the effect of incorporating silver nanoparticles (AgNPs) into conventional orthodontic adhesive on its antibacterial activity and the shear bond strength (SBS) to stainless steel orthodontic brackets. Thirty-four extracted premolars were randomly allocated into two groups (n = 17). Orthodontic adhesive (Transbond XT, 3M Unitek) was blended with AgNPs (50 nm, 0.3% w/w) to form a nano-adhesive. In order to bond stainless steel twin brackets (0.022-inch, American Orthodontics), Transbond XT (n = 17) and nano-adhesive (n = 17) were used in each group, respectively, after acid etching (37% phosphoric acid, 30 s) and rinsing with water (15 s). SBS and the adhesive remnant index (ARI) scores were recorded. Antibacterial activity against Streptococcus mutans in both groups after 24 h and 30 days was assessed (Disc agar diffusion test) and the inhibition zone diameter around each specimen was measured and recorded. Adding AgNPs significantly (p = 0.009) reduced the mean (SD) SBS in the nano-adhesive group [10.51(7.15) MPa] compared to Transbond XT [17.72(10.55) MPa]. The ARI scores on the Transbond XT and nano-adhesive showed no statistically significant difference (p = 0.322). Nano-adhesive with AgNPs showed significant antibacterial activity against Streptococcus mutans at 24 h and 30 days (p < 0.001). In both groups, no significant decline in the zones of inhibition was detected after 30 days (p = 0.907). The findings suggest that SBS decreased after incorporation of AgNPs [0.3% (w/w)], but was still above the recommended SBS of 5.9–7.8 MPa. The nano-adhesive showed significant antibacterial activity which did not change much after 30 days.

Influence of Hydroxyapatite Nanospheres in Dentin Adhesive on the Dentin Bond Integrity and Degree of Conversion: A Scanning Electron Microscopy (SEM), Raman, Fourier Transform-Infrared (FTIR), and Microtensile Study

“…The use of nanoparticles as reinforcing filler improves the mechanical, physical, and working properties of dental composites, as opposed to macro or micro-sized fillers [ 34 ]. The researchers have incorporated various therapeutic ions including silver nanoparticles (AgNPs) [ 35 ], zirconium oxide–titanium dioxide (ZrO 2 -TiO 2 ) nanoparticles [ 36 ], copper-doped bioactive glass nanoparticles (CuBGn) [ 37 ], and n-HA to improve the properties of adhesives [ 38 ]. The n-HA offers superior biocompatibility to act as a source of calcium and phosphate, in addition to possessing a strong ability to bond with tooth proteins [ 38 , 39 ].…”

Antibacterial and white spot lesions preventive effect of an orthodontic resin modified with silver-nanoparticles

“…Recently, Eslamian et al . ( 17 ) demonstrated that the incorporation of AgNPs with a particle size of 50 nm at a concentration of 0.3% into an orthodontic resin had an important activity against S. mutans , this antibacterial property was sTable for 30 days of evaluation. Yassaei et al .…”

“…Silver-nanoparticles (AgNPs) have been used due to their antibacterial properties and low toxicity to human cells. Previous studies have shown that incorporating AgNPs to orthodontic resins has an important antibacterial effect, inhibiting the growth of S. mutans in in vitro models ( 11 , 12 , 17 ). However, to our knowledge its preventive effect on the formation of WSLs has not yet been reported.…”

Evolution of Anticariogenic Resin‐Modified Glass Ionomer Cements

“…These fibers when combined with RMGIC showed a considerable improvement in the flexure strength and fracture toughness. Short glass fibers increased the flexural strength by 50 % whereas long braided fibers significantly enhanced the fracture toughness 69.…”