Evaluation of the signs and symptoms of pseudotumor cerebri syndrome in pediatric population

Sağer, Güneş; Kaplan, Ayşin Tuba; Yalçin, S. Ö.; Çalışkan, Emine; Akın, Yasemin

doi:10.1007/s00381-021-05279-5

Cited by 4 publications

(3 citation statements)

References 28 publications

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“…A study in United Kingdom in 2020 reported a positive correlation between elevated CSF pressure and severity of clinical prognosis 22 . Similarly, a Turkish study reported signi cant positive correlation between the degree of papillary edema and elevated CSF pressure 23 . It has also been reported that obesity is associated with an increase in intraocular pressure and a decrease in ocular pulse amplitude in children and adolescents, independent of insulin resistance 8 .…”

Section: Discussionmentioning

confidence: 75%

The Relationship Between Body Mass Index and Cerebrospinal Fluid Pressure in Children with Pseudotumor Cerebri

Çağ,

Sağer,

Akçay

et al. 2024

Preprint

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Background Childhood obesity has become a major global health problem. Obesity is associated with major health problems, such as diabetes, hypertension, dyslipidemia, cardiovascular disease. Obesity is also considered a risk factor for Pseudotumor cerebri (PTS). The present study aimed to investigate the relationship between body mass index (BMI), and cerebrospinal fluid (CSF) pressure in patients with pseudotumor cerebri. Methods A total of 48 children diagnosed with PTS, who were aged < 18 years and followed up in the pediatric clinic were included in the retrospective study. National BMI percentile curves were used for reference. We investigated statistically the relationship between BMI, clinical and laboratory results, and CSF pressure in patients. Results Of total patients 27 were female (56.25%) and 21 were male (43.75%). With regard to the BMI percentile, 20 (41.67%) were overweight or obese. CSF pressure was higher in overweight and obese patients compared to children with BMI in normal ranges (p < 0.05). A statistically significant positive correlation was also observed between BMI and CSF pressure values and between monocyte and CSF values (p < 0.05). Conclusions The results of the present study indicate a direct relationship between CSF pressure and BMI in children with PTS. Appropriate diet, exercise, and medical treatment in overweight and obese children can make a significant contribution to the treatment of PTS. Additionally, a significant correlation was observed between CSF pressure and monocyte levels.

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Section: Discussionmentioning

confidence: 75%

The Relationship Between Body Mass Index and Cerebrospinal Fluid Pressure in Children with Pseudotumor Cerebri

Çağ,

Sağer,

Akçay

et al. 2024

Preprint

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show abstract

“…Dessardo 21 Tibussek 22 Yamamoto 23 Masri 24 Aylward 25 Female-to-male ratio Prepubertal 3:4 33 Lee et al had pediatric patients who presented with a chief complaint of headache draw representations of their headaches and compared depictions of migraine to those of PIH. 34 They were asked to draw how they felt while experiencing a headache and the location, quality of the pain, and symptoms that appeared before a headache.…”

Section: Clinical Presentationmentioning

confidence: 99%

“…As the most commonly associated symptom, headaches have been studied as a patient‐centered metric in association with IH. Sager et al reported headache worsening while leaning forward or limiting activity as the only symptom correlated with PIH 33 . Lee et al had pediatric patients who presented with a chief complaint of headache draw representations of their headaches and compared depictions of migraine to those of PIH 34 .…”

Section: Clinical Presentationmentioning

confidence: 99%

Pediatric intracranial hypertension: A review of presenting symptoms, quality of life, and secondary causes

Varma,

Aylward

2024

Annals of the Child Neurology Society

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Our understanding of primary (idiopathic) intracranial hypertension has evolved in recent years. There have been efforts to rename the disorder as pseudotumor cerebri syndrome or primary intracranial hypertension. Some studies have suggested a higher threshold opening pressure to define intracranial hypertension. The reported annual incidence varies from 0.6 to 0.9 per 100 000 children around the world. Patients are typically divided into prepubertal and pubertal groups, with pubertal patients having the same risk factors as adults. Prepubertal patients do not share these risk factors. They are more likely to be asymptomatic, have equal gender distributions, and are less likely to be obese. Headache is the most common presenting complaint, followed by vision changes and nausea/vomiting. A newer concept of fulminant intracranial hypertension has emerged, defined as acute onset with rapid progression of visual deficits or papilledema. Quick insertion of a temporary lumbar drain as a bridge while medical management reaches effectiveness improves visual outcomes and helps avoid permanent shunt placement. Headache is typically the first symptom to resolve with treatment, and papilledema resolves in five to six months. Recurrence rates in children and adolescents range from 28.5% to 36.4%, with higher rates after puberty.

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Life-threatening idiopathic intracranial hypertension: the role of venous sinus stenting

et al. 2022

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Evaluation of the signs and symptoms of pseudotumor cerebri syndrome in pediatric population

Cited by 4 publications

References 28 publications

The Relationship Between Body Mass Index and Cerebrospinal Fluid Pressure in Children with Pseudotumor Cerebri

The Relationship Between Body Mass Index and Cerebrospinal Fluid Pressure in Children with Pseudotumor Cerebri

Pediatric intracranial hypertension: A review of presenting symptoms, quality of life, and secondary causes

Life-threatening idiopathic intracranial hypertension: the role of venous sinus stenting

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