2018
DOI: 10.1001/jamapsychiatry.2018.1100
|View full text |Cite
|
Sign up to set email alerts
|

Evaluation of the Social Motivation Hypothesis of Autism

Abstract: Individuals with ASD show atypical processing of social and nonsocial rewards. Findings support a broader interpretation of the social motivation hypothesis of ASD whereby general atypical reward processing encompasses social reward, nonsocial reward, and perhaps restricted interests. This meta-analysis also suggests that prior mixed results could be driven by sample age differences, warranting further study of the developmental trajectory for reward processing in ASD.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

25
205
4
1

Year Published

2018
2018
2021
2021

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 258 publications
(235 citation statements)
references
References 71 publications
25
205
4
1
Order By: Relevance
“…Together with deviant structural and functional connectivity between frontal cortical areas and striatum in autism (46,50,51), structural covariation in striatum and frontal areas may underlie atypical functional fronto-striatal connectivity, and this has been associated with repetitive behavior and executive functioning impairments in autism (3,44). In the present study, the density of caudate nuclei increase simultaneously with densities decreasing on other areas in autism, which fits with the results of a few functional studies that indicate inverse functional changes of these areas (52). Particularly, the special pattern of GM densities changes in frontal and striatal areas might serve an important role in autism-related symptoms.…”
Section: Discussionsupporting
confidence: 89%
“…Together with deviant structural and functional connectivity between frontal cortical areas and striatum in autism (46,50,51), structural covariation in striatum and frontal areas may underlie atypical functional fronto-striatal connectivity, and this has been associated with repetitive behavior and executive functioning impairments in autism (3,44). In the present study, the density of caudate nuclei increase simultaneously with densities decreasing on other areas in autism, which fits with the results of a few functional studies that indicate inverse functional changes of these areas (52). Particularly, the special pattern of GM densities changes in frontal and striatal areas might serve an important role in autism-related symptoms.…”
Section: Discussionsupporting
confidence: 89%
“…Extensive neuroimaging research has implicated the brain's reward network in delay discounting, with individual differences in reward system activation related to behavioral differences in delay discounting and to atypical discounting behaviors in clinical groups (see Peters & Büchel, and Lempert et al, for reviews). Thus, discounting tasks may help inform current debates in the literature about the extent to which ASD is characterized by atypical reward processing (Clements et al, ). Additionally, although delay and social discounting tasks both involve reward processing, only social discounting involves the reward of giving to another, which may recruit social‐cognitive brain networks outside of the reward system (Morelli, Sacchet, & Zaki, ).…”
Section: Introductionmentioning
confidence: 99%
“…All these results suggest that the worsening of social interaction deficits associated with clinical ADHD in children with ASD might be related to the speech processing network in the left SFG. Furthermore, all the evidence supports the importance of the frontal lobe in social processing and social networks [Casartelli & Molteni, ; Clements et al, ; Greimel et al, ; Kana et al, ], which are affected by ADHD comorbidities in children with ASD. However, more research is required to enable the modeling of these systems.…”
Section: Discussionmentioning
confidence: 81%