Evaluation of the subacute toxicity of Yongdamsagan-tang, a traditional herbal formula, in Crl:CD Sprague Dawley rats

Park, Eunsook; Lee, Mee-Young; Seo, Chang‐Seob; Shin, Hyeun‐Kyoo; Han, Sang‐Ik; Ha, Hyekyung

doi:10.1016/j.jep.2019.111852

Journal of Ethnopharmacology

2019

DOI: 10.1016/j.jep.2019.111852

|View full text |Cite

Evaluation of the subacute toxicity of Yongdamsagan-tang, a traditional herbal formula, in Crl:CD Sprague Dawley rats

Eunsook Park

Mee-Young Lee

Chang‐Seob Seo

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Non‐clinical safety evaluation of Yongdamsagan‐tang water extract: A 13‐week subchronic oral toxicity study in Sprague Dawley rats

Jeon,

Seo,

et al. 2024

J of Applied Toxicology

View full text Add to dashboard Cite

Despite the continued clinical application of traditional herbal medicines, scientific evidence such as toxicological safety profile of Yongdamsagan‐tang water extract (YSTW) has not yet been established. The purpose of this study was to investigate the potential toxicity profile of YSTW following a 13‐week repeated oral administration at various concentrations to Sprague Dawley rats. YSTW was administered orally to rats once daily at doses of 0, 1000, 2000, and 5000 mg/kg bw/day for 13 weeks. During the experimental period, there were no significant toxicological changes related to YSTW treatment. These results indicate that the administration of YSTW for 13 weeks in the rat resulted in no signs of toxicity at up to 5000 mg/kg bw/day, which was considered the no‐observed‐adverse‐effect level.

show abstract

Non‐clinical safety evaluation of Yongdamsagan‐tang water extract: A 13‐week subchronic oral toxicity study in Sprague Dawley rats

Jeon,

Seo,

et al. 2024

J of Applied Toxicology

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Evaluation of the subacute toxicity of Yongdamsagan-tang, a traditional herbal formula, in Crl:CD Sprague Dawley rats

Cited by 1 publication

References 22 publications

Non‐clinical safety evaluation of Yongdamsagan‐tang water extract: A 13‐week subchronic oral toxicity study in Sprague Dawley rats

Non‐clinical safety evaluation of Yongdamsagan‐tang water extract: A 13‐week subchronic oral toxicity study in Sprague Dawley rats

Contact Info

Product

Resources

About