Evaluation of the Three Glucometer Devices Performance in Comparison with the Cobas Integra 400 Plus Autoanalyzer in Measuring Blood Glucose Levels: A Comparative Cross-Sectional Study

Abstract

Objective: The study aimed to evaluate the performance of the three glucometers compared to standard the laboratory method (Cobas Integra 400 Plus) in measuring blood glucose levels. Patients and Methods: A total of 100 Yemeni diabetic patients were randomly recruited into a comparative crosssectional study. Venous and finger-pricked blood samples were obtained from all participants and used for blood glucose levels measurement following the standard procedures. Results: The mean blood glucose levels for one-hundred diabetic patients using the Gluco Contour TS and Gluco SD Codefree were not significantly different compared with the Cobas Integra 400 Plus (12.14 ± 6.89 mmol/L vs. 12.85 ± 8.83 mmol/L, P = 0.159; 12.50 ± 7.18 mmol/L vs. 12.85 ± 8.83 mmol/L, P = 0.490), respectively. However, there is a significant difference using the Gluco Alert device from that of the Cobas Integra 400 Plus (11.83 ± 6.94 mmol/L vs. 12.85 ± 8.83 mmol/L, P = 0.046). Furthermore, using the ROC curve at a 95% confidence interval, the Cobas Integra 400 Plus showed a significant agreement with the Gluco Contour TS (51.4%), Gluco SD Codefree (50.4%), and Gluco Alert (39.3%), respectively. For determining accuracy, the sensitivity of the glucometer devices was the following: Gluco SD Codefree (87.3%), Contour TS (85.9%), and Gluco Alert (78.9%). In this regard, the highest specificity was related to Gluco Contour TS (65.5%). Conclusion: The correlation between both me-How to cite this paper: Dahman, L.

Comparative Performance of Different Glucometers for Random Glucose Measurements in Diabetic Patients

“…Studies in Iran reported the stable mean glucose measurements of ABS1 and ABS2 to be 24.3+/-2.4, and 38.8+/-4.5 with a p-value of 0.003 which was statistically signi cant (11) in which. The ndings from Iranian study together with the study by Dahman et al,(21) in the Yemen populations differ from our current study and its ndings as the other two study were carried on records from already known diabetic patients.…”

“…The ndings of this study show that there is a signi cant difference between the mean readings of the glucometers and the laboratory glucose values, with the Accu Chek, Gluco plus and Gluco navii having a positive signi cant direction, their t-value being +2.56, +2.89, +2.41 respectively, and One Touch Plus and Care sense having a negative direction of their mean differences and their variations. This correlated with the ndings by Dahman et al (21) which showed no signi cant difference in blood glucose levels from glucometers when compared with that of the laboratory average values.…”