Evaluation of the wound healing process in rat skin using a hexanoyl group‐modified alkaline‐treated gelatin porous film

Abstract

Oral and maxillofacial surgeries often cause tissue defects, including defects in the epithelium, and may result in scar contracture. Scar contracture in the wound healing process after oral and maxillofacial surgeries may cause facial anomalies, speech issues, and maxillary developmental disorders. 1 Thus, postoperative scar contracture is an important factor that may affect the quality of life of patients undergoing oral and maxillofacial surgeries. 2,3 The wound healing process has four stages: hemostasis, inflammation, proliferation, and maturation. 4,5 Scar contracture is associated with the inflammatory and proliferative phases. 3 The inflammatory stage begins approximately 6 hours after injury. In this stage, various inflammatory cells secrete growth factors and inflammatory cytokines, which promote the growth of fibroblasts and vascular endothelial cells. 6 Wound contraction occurs in the latter half of the proliferative stage, in which granulation tissue starts to form. 4 Wound contraction is regarded as a defense response to the lost

Evaluation of Eruption of Permanent Teeth in Beagle Dog Extraction Sites Filled with Carbonate Apatite

“…For histological analysis, hematoxylin-eosin (HE) staining was performed to observe morphology and tartrate-resistant acid phosphatase (TRAP) staining was performed to observe osteoclasts. Tissue specimens were observed under an optical microscope (BZ-X710; Keyence, Tokyo, Japan) [27].…”