Evaluation of thin‐film photodevices and application to an artificial retina

Kimura, Mutsumi; Shima, Takehiro; Yamashita, T.; Nishizaki, Yoshitaka; Hara, Hiroyuki; Inoue, Satoshi

doi:10.1889/1.2938867

Cited by 15 publications

(8 citation statements)

References 4 publications

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“…The voltage bias (−0.4 to −1.4 V), laser intensity, and laser pulse duration can be tuned to control the amount of photocurrent generated. Similarly, p-i-n and p-n thin-film photodiode 2 nanostructures have been applied to artificial retina [296]. On the other hand, a high-density cell culture array of TiN microelectrodes can be activated by a 150 nm-thick amorphous silicon photoconductor switch [297].…”

Section: Photoelectric Stimulation Electrodesmentioning

confidence: 99%

Nanostructured Coatings for Improved Charge Delivery to Neurons

Kozai

Alba

Zhang

et al. 2014

Nanotechnology and Neuroscience: Nano-Electronic, Photonic and Mechanical Neuronal Interfacing

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This chapter explores the variability and limitations of traditional stimulation electrodes by first appreciating how electrical potential differences lead to efficacious activation of nearby neurons and examining the basic electrochemical mechanisms of charge transfer at an electrode/electrolyte interface. It then covers the advantages and current challenges of emerging micro-/nanostructured electrode materials for next-generation neural stimulation microelectrodes. Introduction to Electrical Stimulation of NeuronsStimulation electrodes have many clinical applications. The most common clinically approved stimulator is the artificial cardiac pacemaker, which is implanted into patients with a slow or arrhythmic heartbeat [1]. Artificial pacemakers use electrodes placed directly in contact with the heart muscles to regulate heart rate by delivering a timed series of electrical pulses. Another common stimulation device implanted into many adults and children is the cochlear implant [2]. Cochlear duct electrodes are designed as a series of stimulation contacts arranged along a flexible silicone carrier (Fig. 4.1a). These electrodes are placed into the cochlea where they directly electrically stimulate nerve cells, bypassing damaged hair cells that transduce acoustic vibrations into electrical impulses in the underlying nerve cells. (Fig. 4.1b). Electrical stimulation in these deep brain structures, such as the basal ganglia, has been used to treat symptoms of Parkinson's disease including tremor and bradykinesia, as well as other movement disorders such as dystonia [3][4][5]. In addition, DBS is being studied as a treatment for stroke, chronic pain, major depression, and chronic obesity [6-10]. For epilepsy and major depression, vagal nerve stimulation offers an alternative that does not require brain surgery [11,12]. In the extremities, functional electrical stimulation (FES) is used to deliver electrical current to activate nerves or muscles in disabled patients. FES has been applied to aid in standing, walking, and basic handgrips and for restoring bowel and bladder function [13][14][15]. Many other electrical stimulation applications exist, including the restoration of somatosensation and vision, the treatment of hypertension and gastroparesis, and the promotion of nerve regeneration [16][17][18][19].While these neurostimulation devices have demonstrated some success in bypassing, replacing, or treating damaged neural circuits, they are far from being able to reliably restore natural function in all patients. In order to understand the variability and limitations of traditional stimulation electrodes, we must first appreciate how electrical potential differences lead to efficacious activation of nearby neurons and examine the basic electrochemical mechanisms of charge transfer at an electrode/electrolyte interface. This chapter will first lay out our current knowledge of these areas and afterwards will cover the advantages and current challenges of emerging micro-/nanostructured electrode materials for ...

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Section: Photoelectric Stimulation Electrodesmentioning

confidence: 99%

Nanostructured Coatings for Improved Charge Delivery to Neurons

Kozai

Alba

Zhang

et al. 2014

Nanotechnology and Neuroscience: Nano-Electronic, Photonic and Mechanical Neuronal Interfacing

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“…[15][16][17][18] The p/i/n TFPTs and TFTs are fabricated on a glass substrate using the usual fabrication processes for lowtemperature poly-Si (LTPS) TFTs. First, the amorphous-Si film is deposited using low-pressure chemical-vapor deposition (LPCVD) of Si 2 H 6 and crystallized using XeCl excimer laser to form the poly-Si.…”

Section: Artificial Retinamentioning

confidence: 99%

P‐1: Artificial Retina Using Thin‐Film Devices

Kimura¹,

Nishizaki²,

Shima³

et al. 2008

Symp Digest of Tech Papers

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“…In our study, we have proposed an artificial retina using poly-Si thin-film transistors (TFTs) [9], [10], which can be fabricated on transparent and flexible substrates. The concept model of the artificial retina fabricated on a transparent and flexible substrate and implanted using epiretinal implant is shown in Figure 1.…”

Section: Introductionmentioning

confidence: 99%

P‐30: Artificial Retina using Poly‐Si Thin‐Film Transistors driven by Wireless Power Supply

Kimura

Miura

Hachida

2011

Symp Digest of Tech Papers

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We have developed an artificial retina using poly-Si thin-film transistors driven by wireless power supply. It is found that the illumination profile can be correctly detected as the output voltage profile even if it is driven using unstable power source generated by inductive coupling, diode bridge, and Zener diodes. This means the feasibility to implant the artificial retina into human eyeballs. P-30 / M. Kimura SID 11 DIGEST • 1201

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Evaluation of thin‐film photodevices and application to an artificial retina

Cited by 15 publications

References 4 publications

Nanostructured Coatings for Improved Charge Delivery to Neurons

Nanostructured Coatings for Improved Charge Delivery to Neurons

P‐1: Artificial Retina Using Thin‐Film Devices

P‐30: Artificial Retina using Poly‐Si Thin‐Film Transistors driven by Wireless Power Supply

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