Evaluation Of Thiol Disulphide Homeostasis And Neutrophile Lymphocyte Ratio In Carbon Monoxide Intoxication:

Tanrıverdi, Fatih; Yüzbaşıoğlu, Yucel; Haydar, Fadime Güllü; Gökhan, Şervan; Özhasenekler, Ayhan; Yıldırım, Çağdaş; Kahraman, Fatih; Eren, Funda

doi:10.5505/amj.2020.71542

Cited by 1 publication

(2 citation statements)

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“…The degree of NLR reduction can aid in determining clinical severity. 40,41 Moon et al found that over the first 12 hours after admission, patients with poor long-term neurological outcome had higher NEU, MON, and NLR levels as well as lower LYM counts than patients with a good outcome. 42 In our study, we found a statistically significant increase in NEUs, WBCs, LYMs, and NLR in COP patients compared with the control group and in the severe poisoning group compared with the mild poisoning group.…”

Section: Discussionmentioning

confidence: 99%

“…Although the number of leukocytes remains constant, a decrease in NEUs and an increase in LYMs can result in a significant decrease in NLR levels. The degree of NLR reduction can aid in determining clinical severity 40,41 . Moon et al found that over the first 12 hours after admission, patients with poor long-term neurological outcome had higher NEU, MON, and NLR levels as well as lower LYM counts than patients with a good outcome 42 .…”

Section: Discussionmentioning

confidence: 99%

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Clinical and Laboratory Characteristics Predicting the Severity of Carbon Monoxide Poisoning in Children

Güven

2023

Pediatr Emer Care

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Objectives: Carbon monoxide poisoning (COP) is extremely common throughout the world. The purpose of this study was to assess the demographic, clinical, and laboratory characteristics predicting the severity COP in children. Methods:The study included 380 children diagnosed with COP between January 2017 and January 2021 and 380 healthy controls. Carbon monoxide poisoning was diagnosed based on the medical history and a carboxyhemoglobin (COHb) level of more than 5%. The patients were classified as mild (COHb 10%), moderate (COHb 10%-25%), or severely (COHb > 25%) poisoned. Results:The mean age of the severe group was 8.60 ± 6.30, for the moderate group was 9.50 ± 5.81, for the mild group was 8.79 ± 5.94, and for the control group was 8.95 ± 5.98. The most common place of exposure was at home and all cases were affected accidentally. The coal stove was the most common source of exposure, followed by natural gas. The most common symptoms were nausea/vomiting, vertigo, and headache. Neurologic symptoms such as syncope, confusion, dyspnea, and seizures were more common in the severe group. A total of 91.3% of the children had hyperbaric oxygen therapy, 3.8% were intubated, and 3.8% were transferred to intensive care in the severe group, whereas no death or sequela was observed. Mean platelet volume and red cell distribution width had the highest area under the curve in the receiver operating characteristic analysis (0.659; 0.379). A positive and low statistically significant relationship was found between COHb levels and troponin and lactate levels in the severe group (P < 0.05).Conclusions: Carbon monoxide poisoning progressed more severely in children presented with neurological symptoms and have elevated red cell distribution width and mean platelet volume. Even in severe COP cases, satisfactory results have been obtained with early and appropriate treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%