Evaluation of thiopyrano[2,3‐d]thiazole derivatives as potential anticonvulsant agents
Eduard Davydov,
Mykhailo Hoidyk,
Sergiy Shtrygol'
et al.
Abstract:Anticonvulsant drug discovery has achieved significant progress; however, pharmacotherapy of epilepsy continues to be a challenge for modern medicine and pharmacy. To expand the chemical space of heterocycles as potential antiepileptic agents, herein we report on the synthesis and evaluation of anticonvulsant properties of a series of thiopyrano[2,3‐d]thiazoles. The studied heterocycles are characterized by satisfactory drug‐likeness and pharmacokinetics properties, calculated in silico using SwissADME. The an… Show more
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