Evaluation of turbo spin echo sequences for MRI of focal liver lesions at 0.5 T

Kreft, Burkhard; Layer, G.; Steudel, A.; Spiller, Laura; Heuck, A.; Müller, A.; Gieseke, Jürgen; Reiser, Maximilian

doi:10.1007/bf00231195

Cited by 10 publications

(9 citation statements)

References 14 publications

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“…Furthermore, they have been proven to generate high image quality, high lesion detectability and conspicuity. We found literature data generally favoring TSE sequences [9], although some reports mention conventional SE sequences as the opti- Fig. 1 a, b. Normal liver parenchyma.…”

Section: Discussionmentioning

confidence: 96%

The influence of MR field strength on the detection of focal liver lesions with superparamagnetic iron oxide

et al. 1997

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The purpose of this study was to compare the value of low- vs high-field MR systems in the detection of focal liver lesions after IV administration of iron oxide particles. A prospective study was undertaken which included 20 patients with focal liver lesions on CT or US, or strong clinical suspicion of focal liver disease. Iron oxide particles were administered in an IV drip infusion over 30 min. Magnetic resonance imaging was subsequently performed on a 0.2 and a 1.5-T system. Both examinations were performed in one session. Turbo spin-echo T2-weighted sequences were used for further analysis (at 0.2 T: TR 4050 ms, TE 96 ms; 1.5 T: TR 3000 ms, TE 103 ms). After randomisation, images were analysed by two blinded readers. The evaluation included lesion counts, determination of lesion conspicuity and overall image quality (both graded on a scale 1-5). Quantitative analysis was performed on 29 lesions. Lesion-to-liver signal intensity and contrast-to-noise ratios (CNRs) were calculated. The total lesion count (cumulative counts for two observers) was 59 on the high-field system and 63 on the low-field system. Statistical analysis showed no significant difference. On both systems median value for lesion conspicuity was 3. No statistically significant difference was found. Global image quality was rated higher on the high-field system: 3 vs 2 for the low-field system (p = 0.0017). Quantitative analysis showed no significant difference for lesion-to-liver signal intensity ratios or CNRs. Although subjective image quality is significantly better on the high-field system, this does not result in better lesion detection or better lesion conspicuity. No significant difference in objective quantitative parameters was found in our series.

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Section: Discussionmentioning

confidence: 96%

The influence of MR field strength on the detection of focal liver lesions with superparamagnetic iron oxide

et al. 1997

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“…Especially on conventional T2-weighted SE images artifacts are most pronounced. Turbo-spin-echo sequences significantly reduce motion-related artifacts [17][18][19], so that even many of the small pulmonary nodules could be diagnosed. In our study 153 nodules (45 %) were ≤ 1 cm in size.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of pulmonary metastases with turbo-SE MR imaging

et al. 1997

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The sensitivity of MR imaging for detection of pulmonary metastases was evaluated in 23 patients. The MR imaging was performed with T2-weighted turbo-spin-echo (TSE) sequences at 1.5 T. The MR images were compared with spiral volumetric CT which served as the radiological standard. All MR images were interpreted by two radiologists without knowledge of CT findings. The MR imaging technique initially enabled correct identification of altogether 286 of 340 metastases (84 %) resulting in sensitivities of 36 % (size of nodules < 5 mm), 83 % (size of nodules 5-10 mm), 92 % (size of nodules 10-15 mm), and 100 % (size of nodules > 15 mm). Retrospectively with knowledge of CT findings an additional 39 metastases were visible; 15 remained undetected even retrospectively. The results of this paper suggest that MRI still does not have a role for screening for pulmonary metastases. It proves, however, that the incidental diagnosis of a pulmonary lesion on T2-weighted TSE images is highly reliable in representing a pulmonary nodule also visible on CT. However, thus far the malignant nature especially of small nodules detected by MRI (as by CT) remains uncertain even in patients with known malignant neoplasm.

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“…Another reason for the use of the heavily T2-weighted TSE se- quence (TR/TE: 5500/150 ms) was the good delineation of the corticomedullary junction. The other advantages of TSE sequences over SE sequences in MRI of the kidneys are identical to those in other abdominal organs, which are shorter imaging time and less artifact susceptibility [22]. To our knowledge, this is the first comparative study of CT and MRI using TSE sequences.…”

Section: Discussionmentioning

confidence: 89%

Diagnostic value of MR imaging in comparison to CT in the detection and differential diagnosis of renal masses: ROC analysis

et al. 1997

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The aim of this work was to compare MR imaging and CT in the detection of renal masses and in the differential diagnosis between benign and malignant lesions. In 33 patients with 54 renal lesions CT and MR images were evaluated by four readers with regard to tumor detection and characterization using a receiver-operating-characteristics (ROC) analysis. The MRI protocol consisted of a T1-weighted spin-echo (SE) sequence (TR/TE: 300/10 ms) before and after contrast administration and a heavily T2-weighted turbo-SE (TSE) sequence (TR/TE: 5500/150 ms). Az values for the area under the ROC curves for lesion detection were 0.92 +/- 0.04 for CT and 0.91 +/- 0.05 for MRI, respectively, which was not statistically different. The MRI technique was slightly, but not significantly, better than CT in the overall characterization (accuracy in differentiation between benign and malignant) of renal lesions with an Az value of 0.90 +/- 0.05 compared with 0.88 +/- 0.06 for CT. The MRI technique proved to be statistically superior to CT (p < 0.01) in the correct characterization of benign renal lesions. MRI equals CT in the overall detection and differential diagnosis of renal masses. MRI is very helpful for further differential diagnosis of lesions which are equivocal on CT especially in the differentiation between complicated cysts and cystic or hypovascular renal cell carcinoma.

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Evaluation of turbo spin echo sequences for MRI of focal liver lesions at 0.5 T

Cited by 10 publications

References 14 publications

The influence of MR field strength on the detection of focal liver lesions with superparamagnetic iron oxide

The influence of MR field strength on the detection of focal liver lesions with superparamagnetic iron oxide

Diagnosis of pulmonary metastases with turbo-SE MR imaging

Diagnostic value of MR imaging in comparison to CT in the detection and differential diagnosis of renal masses: ROC analysis

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