Evaluation of tympanometric alterations in patients subject to general anesthesia with nitrous oxide

Teixeira, Fernanda Mossumez Fernandes; Tomita, Shiro; Lima, Maria Luiza Cunha

doi:10.1016/s1808-8694(15)31323-9

Cited by 10 publications

(7 citation statements)

References 32 publications

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“…These drugs also have placental transitions, and many studies have been conducted on their fetal respiratory functions. It has been reported that the effect of nitrous oxide used as an anesthesia maintenance agent on the acoustic system in adult patients causes increases in intratympanic pressure as well as negative pressure after the termination of anesthesia and secondary fluid accumulation in the middle ear [18]. The study performed for propofol reported that changes in uterine and umbilical blood flows affect placental transition levels of the drug [19].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Anesthesia Type During Delivery on Neonatal Otoacoustic Emission Hearing Test Results: A Tertiary Center Experience

Yakıştıran¹,

Karslı

Canpolat

et al. 2020

Z Geburtshilfe Neonatol

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Background Hearing is essential for the healthy development of an infant as language is one of the main stimulants of intellectual capacity. We investigate the effect of anesthesia type during delivery on neonatal otoacoustic emission (OAE) hearing test results. Methods This retrospective cross-sectional study includes 1,493 healthy, full-term (39/0–40/6 gestational weeks) newborns of healthy women and who were delivered by cesarean section. Newborns were divided into 2 groups based on their anesthesia type during delivery: 1) general anesthesia group (n=160), and 2) spinal anesthesia group (n=1333). Maternal age, anesthesia type, birth weight, gestational age at birth, neonatal gender, 1st–5th minute APGAR scores, and OAE results were compared between the groups. Results 1287 (86.2%) newborns were reported to have passed the first step of OAE; 206 (13.8%) newborns were reported to have failed the first step and passed the second test. In the general anesthesia group, 133 (83.1%) of the newborns passed the first OAE test and 27 (16.9%) newborns had false-positive results. In the spinal anesthesia group, 1,154 (86.6%) of the newborns passed the first OAE test and 179 (13.4%) newborns had false-positive results. The difference between the 2 groups by false-positive values was found to be statistically significant (p<0.001). Conclusions Type of delivery anesthesia may have an effect on the false-positive rates of OAE test results.

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Section: Discussionmentioning

confidence: 99%

The Effect of Anesthesia Type During Delivery on Neonatal Otoacoustic Emission Hearing Test Results: A Tertiary Center Experience

Yakıştıran¹,

Karslı

Canpolat

et al. 2020

Z Geburtshilfe Neonatol

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“…Nose, paranasal sinuses, and nasopharyngeal diseases can disrupt the functions of the ET [15][16][17] . Three mechanisms were postulated for Eustachian tube dysfunction after nasal obstruction: first, airflow turbulence may lead to deposition of microorganisms and air pollutants in the region of Eustachian tube opening, resulting in tubal epithelium or peritubal inflammation and mechanical obstruction.…”

Section: Discussionmentioning

confidence: 99%

“…The use of packing after septoplasty can cause tubal dysfunction because of the edema due to surgery or direct obstruction of the Eustachian tube, but it lasts for a brief time 26 . The general anesthesia also affects the middle ear pressure, but this effect does not last after 17 .…”

mentioning

confidence: 99%

Effect of sinonasal surgery on middle ear pressure

El-bary¹,

Osman²,

El-Oseily³

et al. 2019

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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Introduction: Eustachian tube is often involved in the pathological processes of the nasal, paranasal, and nasopharynx cavities; therefore, nasal obstruction can alter Eustachian tube function (ETF). The pathogenesis of otitis media has been related to the presence of previous or concurrent nasal diseases. Objective: to study whether there are changes in middle ear pressure after sinonasal surgery. Materials and methods: 59 patients who had different nasal pathologies were subjected to History taking, Clinical examination and Tympanometry. ETF tests in the form of valsalva, Toynbee maneuvers and tympanometry had been performed the day before the operation and after 6 weeks. The postoperative middle ear pressure levels were determined using tympanometry. The middle ear pressure values obtained before and after surgery were compared to determine if there is a statistically significant result. Results: There were a significant improvement of nasal obstruction, ear fullness and tinnitus after surgery. The relation between the middle ear pressure preoperatively and at 6 weeks after removal of nasal packs showed a significant improvement in middle ear pressure (P < 0.05) in both ears. Conclusions: Sino-nasal surgery has a favorable effect on the middle ear pressure and Eustachian tube function.

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“…However, N 2 O can increase pressure in closed cavities, such as the middle ear. 12 Increased pressure in the middle ear during tympanoplasty is considered responsible for displacement of the graft. 13 In contrast, we observed that increased middle ear pressure during underlay tympanoplasty with N 2 O anesthesia led to elevation of the perichondrium graft.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Nitrous Oxide on the Outcomes of Underlay Tympanoplasty: A Prospective Study

et al. 2019

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The main aims of tympanoplasty are eradication of chronic middle ear disease, repair of the tympanic membrane, and restoration of hearing. Nitrous oxide (N2O) is not a commonly preferred anesthetic agent for tympanoplasty because this agent may increase middle ear pressure and displace the graft. In this study, we researched the surgical outcomes of the underlay tympanoplasty performed with N2O anesthesia. Patients who underwent tympanoplasty were included in this prospective study. A type 1 tympanoplasty was performed in all patients using the underlay technique. Patients were randomized to groups that did and did not receive N2O. Preoperative and postoperative hearing thresholds were evaluated, postoperative pain scores were recorded, and the differences between the groups were statistically evaluated. There were 44 patients who received N2O and 44 who did not. The graft success rate was 93.2% in the N2O-receiving group and 84.1% in the nonreceiving group ( P > .05). Hearing levels improved significantly after surgery in each group ( P < .05), but the difference between the groups was not significant ( P > .05). The postoperative pain score was 3.72 ± 1.3 in the N2O-receiving group and 4.45 ± 2.3 in the nonreceiving group ( P > .05). Nitrous oxide is a cheap, safe, and readily available anesthetic agent that provides acceptable success rates in patients undergoing tympanoplasty.

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Evaluation of tympanometric alterations in patients subject to general anesthesia with nitrous oxide

Abstract: The nitrous oxide modifies intratympanic pressure during the anesthetic act as well as after it was discontinued.

Cited by 10 publications

References 32 publications

The Effect of Anesthesia Type During Delivery on Neonatal Otoacoustic Emission Hearing Test Results: A Tertiary Center Experience

The Effect of Anesthesia Type During Delivery on Neonatal Otoacoustic Emission Hearing Test Results: A Tertiary Center Experience

Effect of sinonasal surgery on middle ear pressure

The Effect of Nitrous Oxide on the Outcomes of Underlay Tympanoplasty: A Prospective Study

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