Evaluation of USP22 and Ki-67 expression in oral squamous cell carcinoma: An immunohistochemical study
Chelikani Chaitra Apoorva,
Anuradha Ananthaneni,
A. Jagadeesh Kumar
et al.
Abstract:Background and Aim:
USP22 is a positive regulator in tumor growth, its depletion leads to cell cycle arrest at G1 phase. USP22 over expression was positively correlated with proteins involved in proliferation and negatively correlated with tumor suppressor protein tumor supprn. Ki-67 expression is associated with USP22 over expression in oral squamous cell carcinoma (OSCC) and also in cervical and prostate cancers. The aim of this study is to evaluate the expression of USP22 and Ki-67 in OSCC by us… Show more
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