Evaluation of Vaccine Coverage for Low Birth Weight Infants During the First Year of Life in a Large Managed Care Population

Batra, Jagmohan; Eriksen, Eileen; Zangwill, Kenneth M.; Lee, Martin; Marcy, S. Michael; Ward, Joel I.

doi:10.1542/peds.2008-0231

Cited by 44 publications

(48 citation statements)

References 37 publications

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“…Studies conducted in developed countries have obtained similar results (11-14). Langkamp et al found that low birth-weight infants received the first two doses of polio and the first three doses of DPT at significantly older ages than normal birth-weight infants (12).…”

Section: Discusionsupporting

confidence: 64%

“…However, when considering only VLBW infants the immunization levels were significantly lower than normal birth-weight infants (14). This delay is more pronounced during the first year of life and reduced after this (11,12,14). Extremely-low-birth-weight infants are the exception since they continue to receive immunizations at significantly higher ages after 12 months (14).…”

Section: Discusionmentioning

confidence: 96%

“…The mean age for vaccination was more than one month after the recommended age; this is considered the grace period to define the upper limit for age-appropriate vaccination (11,14,16). By 7 months of age all of the evaluated vaccines should have been administered; nevertheless vaccination rates at this age were less than 70%.…”

Section: Discusionmentioning

confidence: 99%

“…More recently Batra et al found that infants with a birth-weight of less than 1500g were less likely to be immunized at an appropriate age compared to normal birth-weight infants. Additionally, extremely-low-birth-weight infants (<1000g) had lower age appropriate immunization rates than larger premature infants (1000-1500g) (11). On the other hand Davis et al concluded than premature infants were vaccinated at levels approaching that of the general population.…”

Section: Discusionmentioning

confidence: 99%

“…Multiple studies in developed countries have shown that premature infants are immunized with a significant delay and it is more pronounced in infants with lower birth-weight (11-14). The most important reasons for this delay are the concerns by parents and providers, including pediatricians, about the immunogenicity and safety of vaccines in preterm infants (2).…”

Section: Introductionmentioning

confidence: 99%

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Vaccine schedule compliance among very low birth weight infants in Lima, Peru

Ochoa

Zea-Vera

Bautista

et al. 2015

Vaccine

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Objective There is little information about vaccine schedule compliance in very-low-birth-weight infants in developing countries. The aim of the study was to describe the compliance with the vaccine schedule among this population in Lima, Peru. Patients and Methods We conducted a prospective cohort study in four hospitals in Lima in infants with a birth-weight of less than 1500g, followed from birth up to 12 months of age every 2 weeks. The date and age at administration of each vacccine was recorded. Results 222 infants were enrolled. The median birth-weight was 1,250g (range 550-1,499g) and the median gestational age was 30.0 weeks (range 23-37 weeks). The mean age for the first pentavalent (DPT, Hib, HepB) and oral polio vaccine administration was 4.3 ± 1.4 months in infants with a birth-weight of <1000g vs. 3.1 ± 1.0 in infants with a birth-weight 1000- 1500g (p<0.001); 4.1 ± 0.9 vs. 3.3 ± 1.1 for rotavirus (p<0.05); and 5.1 ± 2.1 vs. 4.3 ± 1.8 for the 7-valent pneumococcal conjugated vaccine. Only 35% had received the three doses of oral polio and pentavalent vaccine by seven months, although by nine months 81% had received these vaccines. Conclusions Vaccination of very-low-birth-weight infants in Peru is significantly delayed, especially in infants with a birth-weight of <1000g. Urgent educational interventions targeting physicians and nurses should be implemented in order to improve vaccination rates and timing in these high risk populations.

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Section: Discusionsupporting

confidence: 64%

Section: Discusionmentioning

confidence: 96%

Section: Discusionmentioning

confidence: 99%

Section: Discusionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Vaccine schedule compliance among very low birth weight infants in Lima, Peru

Ochoa

Zea-Vera

Bautista

et al. 2015

Vaccine

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On-time Vaccination Coverage in Premature Infants in Ontario, 2002–2009

Wilson

Hawken

Henningsen³

et al. 2012

Can J Public Health

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remature and low birth weight (LBW) children are at increased risk of complications from vaccine-preventable diseases, including pertussis 1 and pneumococcal infection. 2 Consequently, the Public Health Agency of Canada and the American Academy of Pediatrics both recommend that premature and LBW children, if medically stable, should be vaccinated with the routinely recommended childhood vaccines at the same chronological age as full-term infants (i.e., no delay for degree of prematurity) with the exception of the hepatitis B vaccine for infants of HBsAgpositive mothers. 3 Despite expert guidance concerning immunization of premature infants, previous studies have suggested that these infants in general continue to be vaccinated at lower levels when compared to infants born at term. [4][5][6] Within the province of Ontario, Canada, publicly funded immunizations for children include the pentavalent diphtheria, pertussis, tetanus, polio, Haemophilus influenzae type b ([Hib)] (DaPT-IPV-Hib) vaccine along with Pneumococcal conjugate (Pneu-C-7) vaccine given at 2, 4 and 6 months of age. We sought to compare on-time vaccination levels in premature children for these recommended vaccinations to levels in children born at term. METHODSThe purpose of this study was to compare the proportion of term (≥37 weeks gestational age), near term (33-36 weeks), very premature (28-32 weeks) and extremely premature (≤27 weeks) children who received at least one vaccination during the 2-, 4-and 6-month vaccination visits within the recommended time period based on established recommendations. 7 As part of VISION (Vaccine and Immunization Surveillance in Ontario), we examined all children born in Ontario from April 1, 2002 to March 31, 2009 who were present in the Institute for Clinical Evaluative Sciences (ICES) Registered Persons Database (RPDB) -which provides basic demographic information about anyone who has ever received an Ontario health card number -and were eligible for the Ontario

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