Evaluation of Visual Inspection of Cervix with Acetic Acid and Liquid Based in Cervical Cancer Screening with Cervical Biopsy

Shrestha, B; Vaidya, Karishma Malla; Joshi, Rijuta

doi:10.33314/jnhrc.v18i3.1674

Cited by 4 publications

(6 citation statements)

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“…In 2020 Shrestha [12] conducted a study in which researchers performed colposcopy with aqueous AA and delayed histopathological verification in 144 women. Achieved sensitivity, specificity, PPV and NPV accounted for 81%, 65%, 61% and 83%, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…The study confirmed the superiority of liquid diagnostics over the colposcopic evaluation of the cervix. However, the survey concerned a small group of patients [12].…”

Section: Discussionmentioning

confidence: 99%

“…It may be noticed that previous studies have reported discrepancies between colposcopy-directed biopsy (CDB) and LEEP results, with overall concordance or agreement rates ranging from 43% to 86% [10][11][12]. However, study populations and designs, as well as statistical methods, differed among the studies.…”

Section: Introductionmentioning

confidence: 99%

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Histopathological discrepancies between colposcopy-directed biopsy and LEEP-conization observed during SARS-CoV-2 pandemic

Przybylski¹,

Zmaczyński²,

Jach³

et al. 2023

Ginekol Pol

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Objectives: Long-term exposure to the human papillomavirus (HPV) is a known cause of squamous intraepithelial lesions that lead to cervical cancer. The loop electrosurgical excision procedure (LEEP) conization is an established treatment method. According to the latest recommendations, we present a paper to evaluate the effectiveness of various diagnostic methods of squamous intraepithelial lesions. Material and methods: We analyzed 229 patients who reported to District Public Hospital in Poznan to undergo LEEP conization in 2019-2021 during the SARS-CoV-2 Pandemic. The analysis included Pap smear/liquid-based cytology, HPV genotyping, colposcopy with targeted biopsy and LEEP-conization. We offered post-treatment HPV vaccination and, as a follow-up, performed HPV re-genotyping after six months. Results: In total, 89.1% of patients were HPV-positive. The coloscopy-directed biopsy (CDB) results show that almost 70% of the patients had high-grade intraepithelial lesions (HSIL). The diagnosis obtained by LEEP-conization showed that half of the women were diagnosed with HSIL and one-third with the low-grade squamous intraepithelial lesion (LSIL). The sensitivity of Pap smear/LBC accounted for 93.7% and was lower than for CDB, which reached 95.1%. Both diagnostic methods tend to underestimate the final diagnosis. Conclusions:The inclusion of a colposcopic examination in an in-depth diagnostic process in women with abnormal Pap smear results facilitates the identification of patients requiring therapeutic intervention. LEEP-conization may be used without the primary biopsy. It applies to multiparous women in the perimenopausal period, extensive abnormalities, discrepancies in test results, extensive visible abnormalities, and suspicion of invasive cervical cancer in the colposcopic examination.

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Section: Discussionmentioning

confidence: 99%

“…The study confirmed the superiority of liquid diagnostics over the colposcopic evaluation of the cervix. However, the survey concerned a small group of patients [12].…”

Section: Discussionmentioning

confidence: 99%

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Histopathological discrepancies between colposcopy-directed biopsy and LEEP-conization observed during SARS-CoV-2 pandemic

Przybylski¹,

Zmaczyński²,

Jach³

et al. 2023

Ginekol Pol

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“…At multivariable analysis only alcohol consumption and HIV status remained significantly negatively associated with VIA positivity. The prevalence of a positive VIA based on what others have reported ranges from 10-43% [ 10 - 12 ]. Cervical VIA is recommended for low resource settings [ 13 ], it is cheap and its performance is comparable to the Papanicolaou test [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Cervical cancer and precancerous cervical lesions detected using visual inspection with acetic acid at Livingstone Teaching Hospital

Hayumbu¹,

Hangoma²,

Hamooya³

et al. 2021

Pan Afr Med J

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Introduction: cervical cancer (CaCx) is the second most common malignancy in women world-wide. Precancer screening aided by visual inspection with acetic acid (VIA) is an early diagnosis method used to detect the lesions that are high indicators of cancer in women. cervical cancer is more prevalent in the developing world affecting mainly women in the reproductive age group and is the commonest cancer among Zambian women. Therefore, the study aimed to determine the prevalence and factors associated with a positive VIA at Livingstone Teaching Hospital (LTH). Methods: this was a cross-sectional study conducted at LTH among 329 women from Livingstone district aged 18 and above, who were coming for routine cervical cancer screening using VIA between 2019 and 2020. Demographic and clinical data were collected from the CaCx clinic. A positive VIA (precancerous cervical lesions) and cervical cancer were the primary and secondary outcome variables. A positive VIA was defined by presence of a dense ulcerative acetowhite area in the transformation zone of the cervix. Cervical cancer diagnosis was defined by presence of cancerous cells on histological examination by a qualified pathologist. Data were analyzed using Statistical package for social sciences (SPSS) version 22.0. Chi-square test, Mann-Whitney and logistic regression were the statistical methods used. Results: the participants had a median (interquartile range) age of 37 (29, 44) years. Prevalence of CaCx and positive VIA were 6% (95% confidence interval (CI) 4, 9) and 19% (95% CI: 15, 24) respectively. At multivariable analysis, the factors associated with a positive VIA were alcohol consumption [odds ratio (OR) 0.30 (95% CI: 0.12, 0.74)] and HIV infection [OR 0.37 (95% CI: 0.19, 0.70)]. Conclusion: the study showed that precancerous cervical lesions are common among our study participants and it was influenced by alcohol consumption and HIV status. There is therefore need to enhance the screening programs using VIA in order to identify cancerous lesions at an early stage for early intervention in resource limited settings.

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“…[ 3 ] The uses of vinegar are summarized in Table 1 . [ 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 ]…”

Section: Introductionmentioning

confidence: 99%

Home Remedies in Dermatology

Gaurav,

Bhoi,

Mehta

2023

Indian Dermatology Online Journal

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Evaluation of Visual Inspection of Cervix with Acetic Acid and Liquid Based in Cervical Cancer Screening with Cervical Biopsy

Cited by 4 publications

References 0 publications

Histopathological discrepancies between colposcopy-directed biopsy and LEEP-conization observed during SARS-CoV-2 pandemic

Histopathological discrepancies between colposcopy-directed biopsy and LEEP-conization observed during SARS-CoV-2 pandemic

Cervical cancer and precancerous cervical lesions detected using visual inspection with acetic acid at Livingstone Teaching Hospital

Home Remedies in Dermatology

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