Evaluation of vitamin D levels in allergic and non-allergic asthma

Tamašauskienė, Laura; Gasiūnienė, Edita; Lavinskienė, Simona; Sakalauskas, Raimundas; Šitkauskienė, Brigita

doi:10.1016/j.medici.2015.11.003

Cited by 24 publications

(31 citation statements)

References 38 publications

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“…These results are similar with the finding of the Tamašauskienė et al study. 25 In our study, correlation between Vitamin D deficiency and serum calcium, phosphorus and alkaline phosphatase was investigated but no statistically significant relationship was found.…”

Section: Resultsmentioning

confidence: 74%

Effects of 25 hydroxy vitamin D levels on the severity and asthma control in school age asthma patients

2017

Arch Argent Pediat

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Section: Resultsmentioning

confidence: 74%

Effects of 25 hydroxy vitamin D levels on the severity and asthma control in school age asthma patients

2017

Arch Argent Pediat

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“…102,183 This would highlight the role of vitamin D in asthma. 184,185 In children with asthma, an impaired T-reg population with an altered cytokine spectrum and an increase in CD23 þ CD21 þ -expressing B cells has recently been observed. 186 The relationship of allergy with vitamin D deficiency remains a major issue.…”

Section: Role In Acquired and Regulatory Immunitymentioning

confidence: 99%

The Role of Vitamin D in the Immune System as a Pro-survival Molecule

Chirumbolo

Bjørklund

Sboarina

et al. 2017

Clinical Therapeutics

106

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“…Tamašauskienė et al showed no correlations between vitamin D levels and lung function (FEV1, FEV1/FVC) while an inverse positive correlation was noticed between vitamin D level and FEV1/FVC in asthmatic smokers [22]. Columbo et al found no significant association between serum vitamin D and spirometric values even in subjects with lower FEV1% (<70%) and after 12 weeks treatment with 2000 IU vitamin D 3 supplementation [23].…”

Section: Discussionmentioning

confidence: 97%

Study the Potential Antioxidant Effect of Vitamin D3 Supplementation on the Level of Extracellular Superoxide Dismutase in Asthmatic Patients

Abbas

Abdulridha

Shafek

2017

Asian J Pharm Clin Res

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Objective: This study was designed to evaluate the potential antioxidant effect of vitamin D 3 supplementation in chronic asthma patients.Methods: A total of 44 candidate patients were diagnosed with asthma allocated as Group 1 includes 20 patients assigned to receive conventional therapy for asthma and Group 2 includes 24 patients assigned to receive conventional therapy for asthma plus 2000 IU vitamin D 3 tablet for 3-month period. Furthermore, 30 apparently healthy subjects were included in the study as a control group. Pulmonary function test, serum 25-hydroxy vitamin D levels, serum extracellular superoxide dismutase (SOD3) levels were measured before and after 3 months therapy. Results:The mean forced expiratory volume in 1 second (FEV1) both the measured and the percentage of predicted value showed a highly significant increase after 3 months treatment compared to pre-treatment value in both study groups (p<0.01). When compared to pre-treatment value, there was no significant increase in forced expiratory volume in one second to forced vital capacity ratio (FEV1/FVC) in Group 1 (p>0.05), nevertheless, Group 2 showed highly significant increase after 3 months (p<0.01). Approximately, 90-96% of adult asthmatic patients revealed vitamin D deficiency (<20 ng/ml). Post-treatment with adjuvant vitamin D 3 therapy, 25% of patients obtained acceptable level of vitamin D sufficiency (≥30 ng/ml). After 3 months of the treatment, Group 1 patients showed a significant decrease in mean SOD3 level compared to pre-treatment level (p<0.05), while Group 2 patients showed a significant increase in mean SOD3 level compared to pre-treatment level (p<0.05). Conclusion:Most of the asthmatic patients revealed vitamin D deficiency and supplementation with vitamin D3 reduce oxidative stress burden in those patients.

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Evaluation of vitamin D levels in allergic and non-allergic asthma

Cited by 24 publications

References 38 publications

Effects of 25 hydroxy vitamin D levels on the severity and asthma control in school age asthma patients

Effects of 25 hydroxy vitamin D levels on the severity and asthma control in school age asthma patients

The Role of Vitamin D in the Immune System as a Pro-survival Molecule

Study the Potential Antioxidant Effect of Vitamin D3 Supplementation on the Level of Extracellular Superoxide Dismutase in Asthmatic Patients

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