Evaluation of Vitamin D3 level in sino-nasal polypi

Abdel-Rahman, Ali; El-Sobky, Mahmoud El-Said; Rezk, Amr; Emara, Mohamed Salah

doi:10.21608/ijma.2019.17143.1030

Cited by 2 publications

(4 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The purpose of this review is to highlight the effect of VD levels on the pathogenesis and clinical manifestations of CRSwNP/sNP and clarify any therapeutic value of this hormone, in addition to current therapies for CRS. For this review, we managed to collect 20 articles up to July 2023, matching the search criteria with the keywords VD levels, CRS, and nasal polyps [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24].…”

Section: Resultsmentioning

confidence: 99%

“…The other 116 studies were excluded as they related VD levels with other conditions (e.g., allergic rhinitis) and due to other reasons (e.g., written in languages other than English, literature reviews, meta-analyses, case reports, duplication). Although we identified two more eligible records through the manual research of the above-mentioned studies, 20 records were included in the current review [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24].…”

Section: Searching Methodologymentioning

confidence: 99%

“…Abdel-Rahman et al assessed VD levels in patients with nasal polyps, AFRS, CRS, and healthy controls. They concluded that VD may be a low-cost prophylactic and affordable option in the treating arsenal to reduce inflammation, either alone or in collaboration with traditional treatment options, in patients with nasal polyposis [ 22 ].…”

Section: Reviewmentioning

confidence: 99%

See 2 more Smart Citations

Vitamin D Levels in Chronic Rhinosinusitis in Patients With or Without Nasal Polyposis: A Systematic Review

Pantazidou,

Papaioannou,

Skoulakis

et al. 2023

Cureus

View full text Add to dashboard Cite

Chronic rhinosinusitis (CRS) is a large group of heterogeneous diseases characterized by extensive inflammation of the nasal mucosa and sinuses. Vitamin D (VD), as an immunoregulatory hormone, may play an important role in the pathophysiology of CRS. The purpose of this study is to review the existing literature that correlates VD levels with CRS with or without nasal polyps. A systematic manual search was conducted in the PubMed and Google Scholar databases up to July 2023. Articles from PubMed and the first 100 articles from Google Scholar were recorded for our research. Keywords used were the following: vitamin D, chronic rhinosinusitis, and nasal polyps. Among the 134 articles retrieved, only 18 were eligible. The other 116 studies were excluded as they related VD levels with other conditions (e.g., allergic rhinitis) and for other reasons. However, we identified two more eligible records through the manual research of the above-mentioned 132 studies, and finally, 20 records were included in the current review. The review concerned case-control studies, prospective, retrospective, and cross-sectional studies. Based on our review, we concluded that CRS patients are correlated with the lowest VD levels, accompanied by increased severity of the disease, especially in those with nasal polyposis. Patients can benefit from appropriate VD supplementation, and serum VD levels should be included in the laboratory assessment of CRS. However, due to the heterogeneity of the individuals involved, more well-designed clinical trials as well as randomized clinical trials should be conducted for further validation of the above findings in the general population in the future.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Searching Methodologymentioning

confidence: 99%

See 1 more Smart Citation

Vitamin D Levels in Chronic Rhinosinusitis in Patients With or Without Nasal Polyposis: A Systematic Review

Pantazidou,

Papaioannou,

Skoulakis

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…Other than rAOM, Abdel-Rahman et al [33] evaluated the role of vitamin-D levels in patients with Sino-nasal polypi and compared these levels to values of healthy individuals, and reported significant reduction among patients with nasal polypi or allergic rhinitis. They concluded that, vitamin-D is a cheap therapeutic agent which could be used as a prophylactic therapeutic option in reduction of inflammation (working directly by itself or through a synergistic agent besides traditional therapeutic option].…”

Section: Esposito and Leliimentioning

confidence: 99%

Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children

Refaat

Tharwat

El-Gamal

2020

International Journal of Medical Arts

View full text Add to dashboard Cite

Background: Acute Otitis media (AOM) and its recurrence is a prevalent health problem among preschool children. Different strategies to prevent recurrent have been established with questionable efficacy. Vitamin D is suspected as a possible preventable risk factor. Aim of the work: To evaluate the effect of vitamin-D supplementation on recurrence rate of acute otitis media among Preschool children. Patients and Methods: 60 preschool children with a recurrent episode of acute otitis media [by history and otoscopic examination] were included. After diagnosis, all children received standard treatment and after recovery, serum levels of vitamin-D were estimated; those with reduced vitamin D had been included, then divided into: Study group (30 children, received oral vitamin-D supplementation for 4 months; and Control group (30 children; received placebo). New attacks of AOM had been document during the regular visits for the six months. Vitamin D had been re-estimated after 6 months. Results: Both groups were comparable regarding studied variables at the start. Upper respiratory tract infection and ear discharge significantly decreased; vitamin D significantly increased among study group at 6 months. Recurrent AOM after 6 months, had been significantly reduced among study vs control group (1.43±0.62 vs 3.46±0.62 respectively). Also, vitamin-D significantly increased at the end in study vs control group (21.76±5.95 vs 14.53±4.73 ng/ml respectively). The mean percentage of increase of vitamin-D in study group was 135.98% compared to 33.91%. In control group. Conclusion: Vitamin D supplementation to children with a history of rAOM plays a significant role in reduction of attack frequency.

show abstract

Evaluation of Vitamin D3 level in sino-nasal polypi

Cited by 2 publications

References 14 publications

Vitamin D Levels in Chronic Rhinosinusitis in Patients With or Without Nasal Polyposis: A Systematic Review

Vitamin D Levels in Chronic Rhinosinusitis in Patients With or Without Nasal Polyposis: A Systematic Review

Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children

Contact Info

Product

Resources

About