Evaluation of whole lysosomal enzymes directly immobilized on titanium (IV) oxide used in the development of antimicrobial agents

Bang, Seung Hyuck; Jang, Am; Yoon, Jihee; Kim, Pil; Kim, Jong Soo; Kim, Yang‐Hoon; Min, Jiho

doi:10.1016/j.enzmictec.2011.06.004

Cited by 24 publications

(11 citation statements)

References 18 publications

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“…Lysozyme immobilized in polyvinyl alcohol films [66], cellulose [67] and chitosan [68] were effective in inhibiting food spoiling microorganisms. Coating surgical steel blades with a mixture of lysozyme and silver nanoparticles reduced the viability of Klebsiella pneumoniae , B. anthracis, Bacillus subtilis, S. aureus and Acinetobacter baylyi [69]. Lysozyme immobilized on titanium (IV) oxide (TiO 2 ) [70] and on wool fabrics inhibited microorganisms even after washing several times [71].…”

Section: Antimicrobial Enzymes and Microbial Anti‐biofilm Enzymesmentioning

confidence: 99%

Antimicrobial enzymes: An emerging strategy to fight microbes and microbial biofilms

Thallinger¹,

Prasetyo²,

Nyanhongo³

et al. 2013

Biotechnology Journal

292

202

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With the increasing prevalence of antibiotic resistance, antimicrobial enzymes aimed at the disruption of bacterial cellular machinery and biofilm formation are under intense investigation. Several enzyme-based products have already been commercialized for application in the healthcare, food and biomedical industries. Successful removal of complex biofilms requires the use of multi-enzyme formulations that contain enzymes capable of degrading microbial DNA, polysaccharides, proteins and quorum-sensing molecules. The inclusion of anti-quorum sensing enzymes prevents biofilm reformation. The development of effective complex enzyme formulations is urgently needed to deal with the problems associated with biofilm formation in manufacturing, environmental protection and healthcare settings. Nevertheless, advances in synthetic biology, enzyme engineering and whole DNA-Sequencing technologies show great potential to facilitate the development of more effective antimicrobial and anti-biofilm enzymes.

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Section: Antimicrobial Enzymes and Microbial Anti‐biofilm Enzymesmentioning

confidence: 99%

Antimicrobial enzymes: An emerging strategy to fight microbes and microbial biofilms

Thallinger¹,

Prasetyo²,

Nyanhongo³

et al. 2013

Biotechnology Journal

292

202

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“…It was observed that change in the sterilization time increased the Penicillin-G production by 30 % upto 30 minute and only 6% upto 45 minute and then it started to drop. HPLC method was used to carry out quantitative analysis of the product Penicillin G and the precursor Phenyl acetic acid [44,45]. The results further concluded that though the rise in the sterilization temperature increased the Penicillin G production rate, it was cost effective as more energy required to rise the sterilization temperature which in turn increased the cost of production of Penicillin G.…”

Section: Application Of Bioprocess Engineering In Pharmaceuticalmentioning

confidence: 99%

Integrated Application of Bioprocess Engineering and Biotechniques for Quality & Bulk Drug Manufacturing

Jena¹,

Mahalakshmi²,

G³

2011

JBB

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One of the major challenges facing the pharmaceutical industry today is finding new ways to increase productivity, decrease costs whilst still ultimately developing new therapies that enhance human health. Both Biotechniques & Bioprocess engineering are integrated for bulk drug manufacturing of biopharmaceutical products to outcome the above problem. Different biotechnological processes are used in industries for large scale production of biological products for optimization of yield and the quality of end product. Various recent developments in biotechniques and its collaborated work with bioprocess engineering helps to maintain the quality in manufacturing process. However in this review article, we systemically describe all the techniques and different bioprocess used for manufacturing of drugs. To the author's knowledge this review represents the most exhaust description of different biotechniques, different bioprocess, process development and design criteria in bioprocess.

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“…Recently, NPs have become versatile scaffolds to generate excellent supports for enzyme stabilization due to their small size and large surface area. Fe 3 O 4 [8], Fe 2 O 3 [9], ZnO [10], NiO [11], Al 2 O 3 [12], TiO 2 [13], silica [14], gold [15], silver [16] and platinum [17] NPs are often used to immobilize enzymes. NPs strongly influence the mechanical properties of material such as stiffness and elasticity, and provide biocompatible environments for enzyme immobilization.…”

Section: Introductionmentioning

confidence: 99%

In-situ preparation of poly(ether imide)/amino functionalized silica mixed matrix membranes for application in enzyme separation

Sun

et al. 2016

Materials & Design

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Evaluation of whole lysosomal enzymes directly immobilized on titanium (IV) oxide used in the development of antimicrobial agents

Cited by 24 publications

References 18 publications

Antimicrobial enzymes: An emerging strategy to fight microbes and microbial biofilms

Antimicrobial enzymes: An emerging strategy to fight microbes and microbial biofilms

Integrated Application of Bioprocess Engineering and Biotechniques for Quality & Bulk Drug Manufacturing

In-situ preparation of poly(ether imide)/amino functionalized silica mixed matrix membranes for application in enzyme separation

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