Evaluation the oral hygiene conditions, oral Candida colonization and salivary Streptococcus mutans and Lactobacilli density in a group of β-thalassemic children and adolescence

Abstract

Background In this study, the prevalence and distribution of dental caries and oral hygiene conditions in a group of patients with β-TM are evaluated and the results compared to age-and gender-matched healthy patients. In addition, oral candida colonization and the density of Streptococcus mutans (S.mutans) and Lactobacilli in the total saliva are assessed.Material and Methods This study involved 59 β-TM patients between 6-16 years old (mean:11.59±3.22), who applied to the Department of Pedodontics, Faculty of Dentistry, Akdeniz University, with ongoing follow-up, treatment and regular blood transfusions. All enrolled patients were diagnosed with β-TM by the Department of Pediatric Hematology and Oncology, Faculty of Medicine, Akdeniz University. As a control group, age-and gender-matched healthy 50 patients were included to the study.ResultsPlaque (p=0.001), DMFT (p=0.009) and DMFS (p=0.039) indices were significantly higher in the β-TM patients, whereas, the oral hygiene status was significantly lower (p=0.004). Saliva buffering capacity average was insignificantly but slightly more in β-TM patients(p=0.131). While S.mutans values were significantly higher in the β-TM patients (p=0.002), no significant difference was found in the Lactobacillus (p=0.131) and Candida values (p=0.33). Conclusions: DMFT, DMFS, Plaque and oral hygiene indices and S.mutans values were found significantly different in β-TM patients than healthy, control group patients, in this study. Key words:Thalassemia major, DMFT, S.mutans, Lactobacilli, Candida.

Alterations of panoramic radiomorphometric indices in children and adolescents with beta-thalassemia major: A fractal analysis study

“…The records of patients, who presented to the Department of Pedodontics, Faculty of Dentistry, Akdeniz University between 2012 and 2019 for different purposes, were assessed, and 53 ß-TM patients were detected. The DPRIs of the 53 patients were retrospectively obtained from the Department of Oral and Maxillofacial Radiology, Akdeniz University, and the following exclusion criteria were applied: ( 1 ) those who had other systemic diseases in addition to ß-TM; ( 2 ) those who regularly had blood transfusion in Akdeniz University, Faculty of Medicine, Department of Pediatric Hematology-Oncology; ( 3 ) those in whom temporomandibular joint pathology was suspected; ( 4 ) image quality was poor and had horizontal and vertical distortions; ( 5 ) DPRI which had sclerotic area in mandibula; ( 6 ) DPRI with radiologically periodontally unhealthy tissues; ( 7 ) DPRIs in which the mental foramen cannot be clearly visualized, and ( 8 ) DPRIs in which the regions of interest (ROIs) for FD analysis cannot be clearly visualized and images that had anatomical superposition to these areas.…”

“…This disease causes iron overload, marrow expansion, delayed puberty, and hormonal complications, resulting in bone deformity and loss of bone mineral density (BMD) ( 2 ). The common orofacial features contain frontal bossing, skeletal changes because of bony overgrowth (with typical appearances known as chipmunk faces), upper lip retraction, and the protrusion of premaxilla bone associated with alveolar enlargement ( 3 ). This disease leads to an increased prevalence of non-traumatic fractures, both long bone and vertebral ( 2 , 4 ).…”