Evanescent-wave and ambient chiral sensing by signal-reversing cavity ringdown polarimetry

Abstract

Maxwell's equations in isotropic optically active media. In particular, the effective optical rotation path length, near index matching, is equal to the Goos-Hänchen shift 9 of the evanescent wave. The limits of this polarimeter, when using a continuous-wave laser locked to a stable high-finesse cavity, should match sensitivity measurements for linear birefringence (3x10 -13 rad) 10 , which is several orders of magnitude more sensitive than current chiral detection limits 7 , transforming the power of chiral sensing in many fields.

Precision interferometric measurements of mirror birefringence in high-finesse optical resonators

“…Recent demonstrations of background-free CEP, where drifts in mirror birefringence are intentionally negated by the measurement scheme, have reported impressive observations of weak intracavity birefringence for the purpose of quantifying the Kerr effect in gases [41], for detecting parity-nonconserving optical rotation in metastable atoms [42], and for the measurement of optical activity in chiral molecules [43, 44]. In earlier implementations of CEP, however, mirror birefringence remained a significant source of non-negligible background signal [45–50].…”

Simultaneous Chirality Sensing of Multiple Amines by 19F NMR

“…Chemosensory systems designed for chirality determination have attracted increasing attention as a result of their low cost and simplicity as alternatives to traditionally employed X-ray crystallography and chiral chromatography. 2 For instance, on the basis of an intensity change of a fluorescence or circular dichroism (CD) signal, the enantiomeric excess (ee) value of a sample can be quickly evaluated. 3 In addition to the speed of detection, other desirable attributes of a chirality sensing system include simplicity in the measurement, broad substrate applicability, and the ability to analyze complex mixtures.…”

Device-Compatible Chiroptical Surfaces through Self-Assembly of Enantiopure Allenes

“…In order to improve chiroptical sensitivity, extensive efforts have been made in the development of more sophisticated techniques. 51 In this regard, nonlinear chiral effects have been shown to be up to three orders of magnitude larger than the corresponding linear ones. [52][53][54][55] In order to evaluate the chiroptical properties of the CF-2 selfassemblies, we measure second harmonic generation circular dichroism (SHG-CD).…”