In this paper, a [Formula: see text] controller with an event-triggered mechanism is designed for a singular networked cascade control system (SNCCS) under periodic denial-of-service (DoS) attacks. The SNCCS is treated as a system of differential-algebraic equations (DAEs) with an index of two and is modeled as a switched system. The paper first establishes sufficient stability conditions, which are formulated as linear matrix inequalities based on multiple Lyapunov functions. These conditions ensure that the system remains regular, free from impulse modes, and stable. Next, state feedback controllers are designed for both the inner loop and the outer loop. However, the outer loop is subjected to periodic DoS cyber-attacks. Finally, the proposed method’s effectiveness is demonstrated through simulation results on a practical thermal cascade control system.