Evidence against Embryo Transmission of Marek's Disease Virus

Solomon, J. J.; Witter, R. L.; Stone, Howard A.; Champion, L. R.

doi:10.2307/1588646

Cited by 31 publications

(12 citation statements)

References 12 publications

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“…Artificial incubation and rearing is a good preventive measure as vertical transmission of this virus has not been reported (Solomon et al, 1970). The other partridges showed no signs, probably because they came into contact with the virus from the Roulrouls when they already gained age-resistance.…”

Section: Discussionmentioning

confidence: 98%

Marek's disease virus associated ocular lymphoma in Roulroul partridges (Rollulus rouloul)

Haesendonck

Garmyn

Dorrestein³

et al. 2015

Avian Pathology

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Two 1-year old Roulroul partridges (Rollulus rouloul), one male and one female, were presented because of eye problems and anorexia. Twenty of the 30 Roulroul partridges in the owner's collection had already died. The affected birds stopped eating, became thinner, and eventually died. Antibiotic treatment, which started because of the suspicion of a septicaemic process, was unsuccessful. At clinical examination of the two partridges it was found that in both birds, one eye ball was filled with a whitish yellow amorphous material and the other eye ball of the female showed a distinct corneal opacity. Both presented birds were euthanized. Necropsy revealed no significant abnormalities in addition to the eye lesions. Histology and immunohistochemistry of the female's eye revealed an infiltrate of T-lymphocytes corresponding to ocular lymphoma. Herpesvirus genus-specific PCR, followed by Sanger sequencing confirmed the presumptive diagnosis of Marek's disease in both birds. To our knowledge, this is the first confirmed case of infection with Gallid Herpesvirus 2 (Marek's disease virus) in partridges and the first case in this specific species.

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Section: Discussionmentioning

confidence: 98%

Marek's disease virus associated ocular lymphoma in Roulroul partridges (Rollulus rouloul)

Haesendonck

Garmyn

Dorrestein³

et al. 2015

Avian Pathology

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“…Marek virus is known to cause lymphoproliferative disorders with long incubation periods in susceptible chickens (25). Our observation periods might have been too short for their appearance.…”

Section: Discussionmentioning

confidence: 88%

“…Marek virus requires a week or even weeks to induce plaques in chicken-embryo t.e. and is only transferable by means of infected cells, never by media (11,25). Egg cultured Marek virus gives visible takes when inoculated on CAM as well as into the yolk sae (30).…”

Section: Discussionmentioning

confidence: 99%

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Herpesvirus strigis: A new avian herpesvirus

Bürki

Burtscher

Sibalin

1973

Archiv f Virusforschung

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SummaryA virus isolated from dead owls displaying a syndrom called hepato-splenitis infectiosa strigum (IISIS) killed chicken-embryos following inoculation by various routes. Miliary necrotic loci and type A nuclear inclusion bodies were observed on CAM and in embryonic livers and spleens. In chicken-embryo fibroblast tissue cultures syncytia, giant cells and type A nuclear inclusion bodies appeared. These features, as well as biochemical and biophysical properties described in another paper, allowed classification of HSIS virus as an herpesvirus. No serologic crossreaction was observed between HSIS virus on one hand, and infectious laryngotracheitis virus, Marek Virus, and 5 non-avian herpesviruses on the other hand.HSIS virus is therfore considered as a new avian herpesvirus. Herpesvirus st@is is proposed as an appropriate name, since owls of the order strigi/ormes are its natural host.

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“…Control chicks were inoculated with cell culture medium. All chicks were placed by group in modified Horsfall-Bauer isolators supplied with biologically filtered air under negative pressure (Solomon et al, 1970). On the 9th day (8 days post vaccination), the groups were reduced to 15-20 chickens, banded, and challenged with 920 (Expt.…”

Section: Protection Testsmentioning

confidence: 99%