Background: Pedro Ortiz (1933-2011), in the latest four decades of his life, developed the Informational Sociobiological Theory (IST) in a university teaching context that became the foundation of post-grade studies in neuroscience in Peru. The IST looks for a totality explanation of the phenomena of the universe proposes an explanation of the constitution of the human body. In what consist this explanation of the configuration of the human body? Methods: A bibliographical qualitative study was conducted starting from primary documental sources. It was considered among the sources, all related to the editorial project Books of Social Psychobiologic (elaborated by Ortiz during the first decade of this age). The results have been presented across a conceptual analysis, narrative and graphic, oriented to expose Ortiz’ ideas in relation to the human body’s morphology. Results: The structural architecture of the human body, and in particular in one person; shows five levels of complexity which begins in cells, the intercellular matrix, the neural system, the paleocortical psyche, and neocortical psyche. In this involve explanation, the organs of the body are essentially tissue systems, and are integrated (subsumed) at the neural level (which informationally goes through the plexuses, ganglia, and subcortical nuclei). The two levels of superior complexity to the neural system, are the space of the psychic activity, unconscious and conscious, which is suprastructurally to all bodily structures. Ortiz is settled on a different monism: that guides us to imagine and think that all psychic activity is suprastructural to the body. Conclusions: There is an original explanation of the human body within the IST. This informational morphology dialogues with the knowledge of biology, neurology, anatomy, physiology, embryology, and histology, and is proposed as a structuring element in all the conceptual architecture that represents the IST.