Evidence-based validation of herbal medicine: Translational approach

Banerjee, Subhadip; Gupta, Barun Das; Kar, Amit

doi:10.1016/b978-0-323-85542-6.00025-1

Cited by 22 publications

(9 citation statements)

References 95 publications

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“…Also, TM poses a threat to nature for example, most medicinal plants used for wound healing in Uganda are obtained from the wild and this practice could cause extinction of endangered species [ 29 ]. On this basis, efficacy and safety claims of TM needs to be ascertained [ 142 ] and concerted efforts towards addressing other TM associated challenges such as non-standardization are required.…”

Section: Resultsmentioning

confidence: 99%

Medicinal plants used for cutaneous wound healing in Uganda; ethnomedicinal reports and pharmacological evidences

Gang,

Okello,

Kang

2024

Heliyon

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Section: Resultsmentioning

confidence: 99%

Medicinal plants used for cutaneous wound healing in Uganda; ethnomedicinal reports and pharmacological evidences

Gang,

Okello,

Kang

2024

Heliyon

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“…Previous work found that only 15% of synthetic medicines are consumed in developing countries, indicating their dependence on natural remedies. The sale of wild harvested material provides significant income to rural populations . 50–100% of families in the northern region and 25–50% of families in the central region of central Nepal depend on income from medicinal plants. , A compound called rutin has antiviral properties against various influenza viruses. , Quercetin, a potent phytochemical, is effective against a number of viruses such as poliovirus, Epstein–Barr virus, HCV, HSV-1, rhinovirus, adenovirus, etc .…”

Section: Plant-derived Antimicrobials In the Global Marketmentioning

confidence: 99%

“…The sale of wild harvested material provides significant income to rural populations. 37 50−100% of families in the northern region and 25−50% of families in the central region of central Nepal depend on income from medicinal plants. 38,39 A compound called rutin has antiviral properties against various influenza viruses.…”

Section: Global Marketmentioning

confidence: 99%

A Reappraisal of the Antiviral Properties of and Immune Regulation through Dietary Phytochemicals

Thakur,

Singh,

Kumar

et al. 2023

ACS Pharmacol. Transl. Sci.

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In the present era of the COVID-19 pandemic, viral infections remain a major cause of morbidity and mortality worldwide. In this day and age, viral infections are rampant and spreading rapidly. Among the most aggressive viral infections are ebola, AIDS (acquired immunodeficiency syndrome), influenza, and SARS (severe acute respiratory syndrome). Even though there are few treatment options for viral diseases, most of the antiviral therapies are ineffective owing to frequent mutations, the development of more aggressive strains, drug resistance, and possible side effects. Traditionally, herbal remedies have been used by healers, including for dietary and medicinal purposes. Many clinical and scientific studies have demonstrated the therapeutic potential of plant-derived natural compounds. Because of unsafe practices like blood transfusions and organ transplants from infected patients, medical supply contamination. Our antiviral therapies cannot achieve sterile immunity, and we have yet to find a cure for these pernicious infections. Herbs have been shown to improve therapeutic efficacy against a wide variety of viral diseases because of their high concentration of immunomodulatory phytochemicals (both immunoinhibitory and anti-inflammatory). Combined with biotechnology, this folk medicine system can lead to the development of novel antiviral drugs and therapies. In this Review, we will summarize some selected bioactive compounds with probable mechanisms of their antiviral actions, focusing on the immunological axis of these compounds.

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“…Its root, stems and leaves are used in Ayurvedic medicine and has shown immense application in the treatment of various diseases. It is shown to possess pharmacological actions like anticancer, antiulcer, antiischemic, cardiotonic, anti-inflammatory, antispasmodic, antiarthritic, analgesic and diuretic properties (Mukherjee et al, 2022). The pharmacological actions are due to the presence of major phytoconstituents viz., tinosporaside, tinosporone, tinosporic acid and cordifolisides A to E. It is also a source of natural antioxidants Srivastava, 2021).…”

Section: Introductionmentioning

confidence: 99%

Phyto-assisted synthesis of Silver nanoparticles using Tinospora cordifolia leaf extract and their antibacterial activity: An ecofriendly approach

Phanse,

Venkataraman,

Kekre

et al. 2024

Braz. J. of Sci.

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To meet the increasing demands for commercial nanoparticles new eco-friendly methods of synthesis are being discovered. Plant mediated synthesis of nanoparticles offers single step, easy extracellular synthesis of nanoparticles. We report the synthesis of antibacterial Silver nanoparticles using leaf extract of the medicinal plant, Tinospora cordifolia. The leaf extract was prepared by boiling chopped leaves of Tinospora cordifolia in deionized water for 10 min and filtering the mixture with Whatman filter paper No.1. The filtrate was used as a reducing agent and stabilising agent for AgNO3. On adding 1 mM solution of Silver nitrate to the leaf extract and stirring at 75 °C for 25 min, a change in colour from yellow-brown to brown-black specified the production of Silver nanoparticles. The formation of Silver nanoparticles was monitored by UV-visible spectroscopy and further characterization of the synthesized Silver nanoparticles was done by XRD studies. The antibacterial studies were performed on Gram negative and Gram positive pathogens, Salmonella typhi, Pseudomonas aeruginosa, Enterobacter aerogenes and Staphylococcus aureus, by agar well diffusion method, on Mueller Hinton agar medium. The Silver nanoparticles synthesized from Tinospora cordifolia leaf extract were found to have antimicrobial activity against these Gram negative and Gram positive pathogenic bacteria.

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Evidence-based validation of herbal medicine: Translational approach

Cited by 22 publications

References 95 publications

Medicinal plants used for cutaneous wound healing in Uganda; ethnomedicinal reports and pharmacological evidences

Medicinal plants used for cutaneous wound healing in Uganda; ethnomedicinal reports and pharmacological evidences

A Reappraisal of the Antiviral Properties of and Immune Regulation through Dietary Phytochemicals

Phyto-assisted synthesis of Silver nanoparticles using Tinospora cordifolia leaf extract and their antibacterial activity: An ecofriendly approach

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