“…19,21 This study revealed that compared with ropivacaine alone, perineural or IV dexmedetomidine can reduce VAS scores at rest and movement and Prince-Henry Pain scores at 12 and 24-h after surgery, and reduce the consumption of intraoperative and postoperative OME, which was consistent with previous studies. 40 QoR-15 is a validated quality assessment tool, and the results demonstrated that perineural and IV dexmedetomidine can improve the QOD-15 score at POD1 compared with ropivacaine alone, which has achieved minimum clinically important difference (MCID) (6.0). 41 Another important result of our study was the effect of perineural dexmedetomidine compared to IV dexmedetomidine.…”