Evidence for a Positive Association Between Pulmonary Function and Wine Intake in a Population-Based Study

Grant, Brydon J. B.; Freudenheim, Jo L.; Muti, Paola; McCann, Susan E.; Kudalkar, Deepa; Ram, Malathi; Nochajski, Tom; Russell, Marcia; Trevisan, Maurizio

doi:10.1007/s11325-002-0161-6

Cited by 7 publications

(4 citation statements)

References 40 publications

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“…Indeed, a previous study from the same TESAOD cohort that used baseline alcohol and lung function parameters found heavy drinking to be associated with respiratory symptoms, particularly in association with heavy smoking (Lebowitz, 1981). In contrast, studies that included subjects with varied levels of alcohol intake have provided different, and somewhat inconsistent, results with some showing no association of alcohol with lung function after accounting for smoking status (Cohen et al, 1980; Sparrow et al, 1983), others showing negative associations (Lange et al, 1988; Zureik et al, 1996), but the majority showing enhanced lung function among light to moderate drinkers (Root et al, 2014; Schunemann et al, 2002; Sisson et al, 2005; Siu et al, 2010; Tabak, Smit, Heederik, et al, 2001; Tabak, Smit, Rasanen, et al, 2001; Twisk et al, 1998). These inconsistencies may be related to large inter-study differences in alcohol intake, age distributions, study design, and heterogeneity in other relevant demographic, clinical, and behavioral factors.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have found that moderate alcohol intake is associated with increased lung function measures – particularly forced vital capacity (FVC) and forced expiratory volume in one second (FEV 1 ) – in the general population, but these findings have not always been consistent even after taking into account possible confounders like concomitant cigarette smoking (Cohen et al, 1980; Frantz, Wollmer, Dencker, Engstrom, & Nihlen, 2014; Garshick, Segal, Worobec, Salekin, & Miller, 1989; Lange et al, 1988; Root, Houser, Anderson, & Dawson, 2014; Schunemann et al, 2002; Sisson et al, 2005; Siu, Udaltsova, Iribarren, & Klatsky, 2010; Sparrow, Rosner, Cohen, & Weiss, 1983; Tabak, Smit, Heederik, Ocke, & Kromhout, 2001; Tabak, Smit, Rasanen, et al, 2001; Twisk, Staal, Brinkman, Kemper, & van Mechelen, 1998; Zureik, Liard, Kauffmann, Henry, & Neukirch, 1996). A possible explanation for these discrepancies is that the relation of alcohol intake to lung function is largely dependent on both the quantity and duration of alcohol consumption.…”

Section: Introductionmentioning

confidence: 99%

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Persistent light to moderate alcohol intake and lung function: A longitudinal study

Vasquez

Sherrill

LeVan

et al. 2018

Alcohol

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Alcohol intake has been inconsistently associated with lung function levels in cross-sectional studies. The goal of our study was to determine whether longitudinally assessed light-to-moderate alcohol intake is associated with levels and decline of lung function. We examined data from 1333 adult participants in the population-based Tucson Epidemiological Study of Airway Obstructive Disease. Alcohol intake was assessed with four surveys between 1972 and 1992. Subjects who completed at least two surveys were classified into longitudinal drinking categories ("never", "inconsistent", or "persistent drinker"). Spirometric lung function was measured in up to 11 surveys between 1972 and 1992. Random coefficient models were used to test for differences in lung function by drinking categories. After adjustment for sex, age, height, education, BMI categories, smoking status, and pack-years, as compared to never-drinkers, persistent drinkers had higher FVC (coefficient: 157 mL, p < 0.001), but lower FEV/FVC ratio (-2.3%, p < 0.001). Differences were due to a slower decline of FVC among persistent than among never-drinkers (p = 0.003), and these trends were present independent of smoking status. Inconsistent drinking showed similar, but weaker associations. After adjustment for potential confounders, light-to-moderate alcohol consumption was associated with a significantly decreased rate of FVC decline over adult life.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Persistent light to moderate alcohol intake and lung function: A longitudinal study

Vasquez

Sherrill

LeVan

et al. 2018

Alcohol

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“…Our finding of a relationship between higher alcohol consumption and a slower decline in FEV 1 seems peculiar. Lange et al 42 found that the effect on FEV 1 decline by a high alcohol consumption (350 g per week or more) was equivalent to 15 g of tobacco daily, while Schünemann et al 43 found no correlation between total alcohol consumption and lung function decline, but on the other hand a positive relationship between wine drinking and change in FEV 1 , which is most likely due to confounding by a healthier lifestyle in wine drinkers. The mean weekly consumption in our cohort was around 130 g, and by that substantially lower than that in the cohort of Lange et al, 42 which may explain some of the differences in observations.…”

Section: Discussionmentioning

confidence: 99%

Predictors of accelerated FEV₁ decline in adults with airflow limitation—Findings from the Health2006 cohort

et al. 2019

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To investigate predictors of accelerated decline in forced expiratory volume in 1 s (FEV 1 ) in individuals with preexisting airflow limitation (AL). Participants in the Health2006 baseline study aged ≥ 35 with FEV 1 / forced vital capacity (FVC) < lower limit of normal (LLN) were invited for a 10-year follow-up. At both examinations, data were obtained on demographics, spirometry, fitness level, allergy, and exhaled nitric oxide. We used multiple regression modeling to predict the annual decline in FEV 1 , reported as regression coefficients ( R ) and 95% confidence intervals (CIs). A total of 123 (43% of those invited) participated in the follow-up examination, where more had exercise-induced dyspnea but fewer had asthma symptoms. Being female ( R = −29.8 ml, CI: −39.7 to −19.8), diagnosed with asthma ( R = −13.7, CI: −20.4 to −7.0) or atopic dermatitis ( R = −29.0, CI: −39.7 to −18.4), and having current asthma symptoms or nightly respiratory symptoms ( R = −22.1, CI: −31.9 to −12.4 and R = −14.3, CI: −19.9 to −8.7, respectively) were significantly associated with a steeper decline in FEV 1 . Although to a smaller extent, a steeper decline was also predicted by age, baseline FEV 1 , waist/hip-ratio, and number of pack-years smoked. In individuals with preexisting AL, being female and having ever or current respiratory symptoms were associated with an accelerated annual decline in FEV 1 .

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“…11 Based on biological considerations, moderate drinking could exhibit beneficial effects on CRF by increasing insulin sensitivity, anti-inflammatory effects, enhancing levels of high-density lipoprotein cholesterol and adiponectin, improving pulmonary function, and by lowering of fibrinogen and lower blood pressures. 35–37 Several detrimental actions of alcohol might explain lower CRF among participants with high average alcohol intake, including suppressed fat oxidation leading to insulin resistance, hypertriglyceridaemia, and weight gain and adiposity; inhibition of the pulmonary immune response and airway epithelial permeability, and airway leakage; decrease amount of glucose and amino acids used by the skeletal muscles with decrease in energy supply; decreased muscle capillarity, lower glycogen utilization levels; lower fatty acids; lower liver glucose output; and ethanol-induced hypoglycaemia. 38–40…”

Section: Discussionmentioning

confidence: 99%

Alcohol consumption and cardiorespiratory fitness in five population-based studies

Baumeister

Finger

Gläser

et al. 2017

Eur J Prev Cardiolog

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Background Poor cardiorespiratory fitness is a risk factor for cardiovascular morbidity. Alcohol consumption contributes substantially to the burden of disease, but its association with cardiorespiratory fitness is not well described. We examined associations between average alcohol consumption, heavy episodic drinking and cardiorespiratory fitness. Design The design of this study was as a cross-sectional population-based random sample. Methods We analysed data from five independent population-based studies (Study of Health in Pomerania (2008-2012); German Health Interview and Examination Survey (2008-2011); US National Health and Nutrition Examination Survey (NHANES) 1999-2000; NHANES 2001-2002; NHANES 2003-2004) including 7358 men and women aged 20-85 years, free of lung disease or asthma. Cardiorespiratory fitness, quantified by peak oxygen uptake, was assessed using exercise testing. Information regarding average alcohol consumption (ethanol in grams per day (g/d)) and heavy episodic drinking (5+ or 6+ drinks/occasion) was obtained from self-reports. Fractional polynomial regression models were used to determine the best-fitting dose-response relationship. Results Average alcohol consumption displayed an inverted U-type relation with peak oxygen uptake ( p-value<0.0001), after adjustment for age, sex, education, smoking and physical activity. Compared to individuals consuming 10 g/d (moderate consumption), current abstainers and individuals consuming 50 and 60 g/d had significantly lower peak oxygen uptake values (ml/kg/min) (β coefficients = -1.90, β = -0.06, β = -0.31, respectively). Heavy episodic drinking was not associated with peak oxygen uptake. Conclusions Across multiple adult population-based samples, moderate drinkers displayed better fitness than current abstainers and individuals with higher average alcohol consumption.

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Evidence for a Positive Association Between Pulmonary Function and Wine Intake in a Population-Based Study

Abstract: While total alcohol intake was not related to lung function, wine intake showed a positive association with lung function. Although we cannot exclude residual confounding by healthier lifestyle in wine drinkers, differential effects of alcoholic beverages on lung health may exist.

Cited by 7 publications

References 40 publications

Persistent light to moderate alcohol intake and lung function: A longitudinal study

Persistent light to moderate alcohol intake and lung function: A longitudinal study

Predictors of accelerated FEV₁ decline in adults with airflow limitation—Findings from the Health2006 cohort

Alcohol consumption and cardiorespiratory fitness in five population-based studies

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Evidence for a Positive Association Between Pulmonary Function and Wine Intake in a Population-Based Study

Abstract: While total alcohol intake was not related to lung function, wine intake showed a positive association with lung function. Although we cannot exclude residual confounding by healthier lifestyle in wine drinkers, differential effects of alcoholic beverages on lung health may exist.

Cited by 7 publications

References 40 publications

Persistent light to moderate alcohol intake and lung function: A longitudinal study

Persistent light to moderate alcohol intake and lung function: A longitudinal study

Predictors of accelerated FEV1 decline in adults with airflow limitation—Findings from the Health2006 cohort

Alcohol consumption and cardiorespiratory fitness in five population-based studies

Contact Info

Product

Resources

About

Predictors of accelerated FEV₁ decline in adults with airflow limitation—Findings from the Health2006 cohort