Evidence for a separate type of migraine with aura

Thomsen, Laura H.; Østergaard, Elsebet; Olesen, Jes; Russell, Michael Bjørn

doi:10.1212/01.wnl.0000046524.25369.7d

Cited by 116 publications

(163 citation statements)

References 33 publications

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“…26,27 Most patients also experience typical aura symptoms during an attack, usually sensory, as this patient did. 26 The hemiplegia is almost always accompanied by head pain, unlike other auras (e.g., visual), which can occur without headache. 27 The pathophysiology of motor aura is now being explored with mouse models as the genes have been identified.…”

Section: Migraine With Aura In Childrensupporting

confidence: 51%

“…There is no biphasic symptom progression, specifically no jerking before the onset of weakness. 12 While most attacks come on over minutes, 7% of patients experience onset of weakness in under 1 minute, 26 as this patient did. The weakness is twice as likely to affect the arm as the leg.…”

Section: Migraine With Aura In Childrensupporting

confidence: 49%

“…The weakness is twice as likely to affect the arm as the leg. 26 Duration can be hours to days, though most still resolve within an hour. 26,27 Most patients also experience typical aura symptoms during an attack, usually sensory, as this patient did.…”

Section: Migraine With Aura In Childrenmentioning

confidence: 99%

“…26 Duration can be hours to days, though most still resolve within an hour. 26,27 Most patients also experience typical aura symptoms during an attack, usually sensory, as this patient did. 26 The hemiplegia is almost always accompanied by head pain, unlike other auras (e.g., visual), which can occur without headache.…”

Section: Migraine With Aura In Childrenmentioning

confidence: 99%

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Child Neurology: Migraine with aura in children

Gelfand¹,

Fullerton²,

Goadsby³

2010

Neurology

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The differential diagnosis for an acute hemiparesis in a child includes stroke, Todd paralysis, and hemiplegic migraine. In the context of an illustrative case, this review highlights the differences in clinical presentation among these entities and an approach to the diagnostic workup. Migraine with aura in children is reviewed, including migraine equivalents such as abdominal migraine and the particular presentation of hemiplegic migraine. An approach to the prophylactic and acute treatment for children with migraine with aura is offered. Neurology ® 2010;75:e16 -e19 CASE: PART 1 A 14-year-old boy with Crohn disease was admitted for a presumed flare. On the second hospital day, his abdominal pain acutely increased. Shortly thereafter, he experienced tingling starting in his shoulder and spreading over his left hemibody over 10 seconds. This was accompanied by 7/10 pounding left-sided head pain. Several minutes later, the tingling gave way to diminished sensation and weakness on the left. These symptoms persisted into the next morning, at which time a neurologic consultation was requested. Now 20 hours into the attack, he had 5/10 pounding head pain. Neurologic examination revealed a left hemiparesis in a pyramidal distribution, with face and arm affected more than leg. Sensation was also diminished over the left face and hemibody. Reflexes were normal and there was no neglect. Complete blood count, electrolytes, erythrocyte sedimentation rate, liver function tests, lactate, amylase, and lipase were normal.

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Section: Migraine With Aura In Childrensupporting

confidence: 51%

Section: Migraine With Aura In Childrensupporting

confidence: 49%

Section: Migraine With Aura In Childrenmentioning

confidence: 99%

Section: Migraine With Aura In Childrenmentioning

confidence: 99%

See 2 more Smart Citations

Child Neurology: Migraine with aura in children

Gelfand¹,

Fullerton²,

Goadsby³

2010

Neurology

View full text Add to dashboard Cite

show abstract

“…Thus, at least four genes can cause familial hemiplegic migraine, i.e., genetic heterogeneity. In order to make it even more complex, the phenotype of familial hemiplegic migraine is mimicked by sporadic hemiplegic migraine [4]. As few sporadic hemiplegic migraine cases are caused by mutations in the known genes, the majority of cases may have another cause.…”

mentioning

confidence: 99%